HBIO Lecture 4 Evolution Flashcards
things required for evolution (4)
inherited variation (is needed for natural selection to occur)
system of reproduction
changing environment
selective pressures
differential reproductive success (fitness)
biotic factors selection pressures
competition
predation
disease
abiotic factors selection pressures
climate
topography, e.g. a landslide
habitat
how do selection pressures occur
act on the phenotype
act on all stages of the life cycle
may act for many generations
selection pressure that impacts the elderly will have a weaker force than one that impacts foetuses or pregnant women.
differential reproduction
survival + reproduction = fitness
more offspring in the future = greater evolutionary fitness
example of natural selection in humans
native puna indians in argentinian andes, have a high level of arsenic tolerance
cold climates, large stocky body with short limbs
hot climates, smaller bodyweight with longer limbs
this is about heat loss of protection against heat loss
climate has determined body size
are we still evolving
yes, evidence of HIV resistance in regions of Africa
humans have modified their environments in ways that have relaxed selection pressures on many traits
clean water
access to medicines and vaccines
more reliable supply of food
how is evolution relevant (4)
evolutionary medicine - uses evolutionary theory to understand health, disease & anatomy
emerging diseases, e.g. COVID-19 & SARS (2002)
origins of disease
- e.g. HIV and SIV share common viral ancestor
- origins of disease instruct our research
treatment of disease
antibiotic resistance
vaccines need to change
drug cocktail
drug development
sources of compounds for drugs
testing on animals with shared common ancestor
mode of transmission relates to the effect of the disease
historically advantageous genes become detrimental in the modern world haemochromatosis
evolutionary trade-offs
skin pigmentation:
UV protection of folate levels vs vitamin D synthesis
conservation biology
low population numbers = low genetic variation of the gene pool