Halo Flashcards
Hunsdiecker reaction is a?
free radical reaction
The dipole moment of CH3X (where X is a halogen) follows the order
CH3Cl > CH3F > CH3Br
If sodium in ethanol is used for the reduction of aldehydes, ketones and esters, the reaction is known as
Bouveault-Blanc reduction
Benzoyl derivatives or esters of phenol can be made by reaction of phenol with benzoyl
chloride in presence of 10% NaOH solution. This is known as
Schotten-Baumann reaction.
Carbonyl carbon is a Lewis _____, and carbonyl
oxygen, a Lewis ________.
acid
base
Stephen reaction halide?
SnCl2
alternatively, DIBAl H to convert to imines
Gattermann Koch catalyst
AlCl3/CuCl
Nu attacks carbonyl compound from?
above
Fehling solution A is aqueous ______ and Fehling solution B is alkaline_______ (Rochelle salt).
copper sulphate
sodium potassium tartarate
Carboxyl angle?
120
RMgX with CO2
carboxylic acid
For amines
C-N-E angle is _____
trimethylamine angle
109.5
108
How many Br2 and NaOH in hoffman
1 Br2
4NaOH
Carbylamine reaction no. of KOH
3KOH
Chloramphenicol used for
Typhoid
For alkyl bromide preparation, alcohol is boiled with __% HBr
48
___% orthophosphoric acid for RI
95
Who proposed mechanism for SN2 reaction
Edward Hughes and Christopher Ingold
Relative rates of methyl, ethyl, isopropyl and tert-butyl SN2 reactions
30, 1, 0.02, 0
Who first observed polarisation in organic
Louis Pasteur
Who introduced chirality
Le Bel and Van’t Hoff
bulkier nucleophiles give _________ reactions
elimination
due to steric reasons
In replacement of chlorine by hydroxyl group, the fast and slow reactions for chloronitrobenzenes
slow: addition of -OH to the compound
fast: loss of chlorine
Why doesn’t metanitrochlorobenzene have any effect on reaction rate?
negative charge does not come to the carbon attached to the nitro group, so there’s no effective EWG effect
Reactivity of chlorobenzenes is controlled by the _________ and orientation is controlled by ____
stronger inductive effect
resonance effect
Chloroform is used in the production of which CFC
freon R-22
chloroform exposure hurts the liver because
it is metabolized to phosgene there
