Haemoglobin Flashcards
Types of haemoglobin
A, A2,F
What does it consist of ?
Iron containing haem group
4 protein chains
Haemoglobin A
98% of adult haemoglobin
2 alpha chains
2 beta chains
Thalassemia
Caused by a default in a gene ( in chromosome 11)
Symptoms
Anaemia - RBC have a short life
Liver and spleen enlargement - remove abnormal RBC.
Too much iron in organs - body is overwhelmed with breakdown products
What is it made more out of - alpha or beta ?
Alpha chains due to them being more flexible
This flexibility will help carry oxygen around the blood
What are the differences alpha and beta?
Alpha helices had their amino acids bonded and arranged in a way which allows them to be flexible. This may help to transport substances around the blood.
Beta pleated sheet have their amino acids being bonded strong and rigid. This will usually help in structural proteins for strength.
What are blue loops and what are they?
Carry oxygen in blood
An example of protein; it’s function ;how structure contributes to function?
Cytochrome
Electron carrier in electron transport chains which is a stage of aerobic cellular respiration
What effect does changing the esker size have on the rate of diffusion ?
Greater the surface area: volume ratio the greater the rate of diffusion . More room for particles to spread out. More need to fill space. More diffusion