haematology

Question 1

Blood film findings

target cells

Answer 1

sickle cell anaemia 
thalassaemia 
iron deficiency 
hyposplenism 
liver disease

Question 2

tear drop

Answer 2

myelofibrosis

Question 3

spherocytes

Answer 3

autoimmune haemolytic anaemia

Question 4

basophilic stipling

Answer 4

lead
thalassaemia
sideroblastic anaemia
myelodysplasia

Question 5

howell jolly bodies

Answer 5

hyposplenism

Question 6

heinz body

Answer 6

g6pd

Question 7

schistocytes

Answer 7

Intravascular haemolysis
mechanical heart valves
DIC

Question 8

pencil

Answer 8

iron deficiency

Question 9

burr cells

Answer 9

uraemia

Question 10

mature plasmacytic cells with clumped chromatin

nuclear to cytoplasmic ration
abundant cytoplasm and rare nuceli?

Answer 10

mature myeloma cells

Question 11

plasmablastic cells with prominent nucleoli reticular chromatin

Answer 11

immature myeloma cellls

Question 12

bence jones protein?

Answer 12

free light chains in blood and when tested and found in urine called the

Question 13

smudge cells?

what does this cancer present with?

Answer 13

CLL

incidental leukocytosis

Question 14

burr cells

Answer 14

look like spikes and occur with uraemia

Question 15

beta thalassaemia minor

Answer 15

1 func and 1 dysfunctional
microcytosis and mild anaemia
asymptomatic

Question 16

beta thalassaemia major

Answer 16

3-9 months anaemia presents
frontal mossing
naxillary overgrowth
hepatosplenomegaly

death by HF is undiagnosed

mx: regulr blood transfussion and iron chelators

Question 17

causes of massive splenomegaly?

Answer 17

thalassaemia
CML
polycythaemia
kala azar

Question 18

does EBV cause massive splenomegaly?

Answer 18

no just medium / mild