endo Flashcards

1
Q

Mx of acromegaly

A

transphenoidal surgery

bromocriptine beforehand

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2
Q

sudden headache
vomiting
visual disturbances
hormonal dysfunction

bitemporal quadrantanopia

A

pituitary apoplexy

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3
Q

normal anion gap suggests?

A

diarrhoea
renal tubular acidosis
hyperparathyroidism

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4
Q

elevated anion gap?

A

unmeasure anion is in increased quantities like lactate or ketones
lactic acidosis
ketoacidosis
salicylate overdose

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5
Q

what is the difference between insulin overdose / hypoglycaemic coma ?

A

too much insulin adminstration

in coma - you just have not eaten enough glucose for the insulin regime

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6
Q

nelson syndrome

A

biltaeral adrenalectomies - macroadenoma in pituitary which secretes ACTH

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7
Q

most appropriate investigation for Thyroid?

A

TSH

T4/t3

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8
Q

what is amyotrophy - diabetic?

A

wasting of muscles, painful quadriceps

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9
Q

SIADH features

A

reduced sodium
urine osmolality is raised

reduced serum osmolality - euvolemic

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10
Q

DI features

A

large volumes of dilute urine
low urine osmolality
nocturia and thirst

serum osmolality is raised but urine is dilute

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11
Q

dilute urine
concentrated serum osmolality

> 700 is relevant why

desmopressin given and urine does not get more concentrated

A

> 700 urine osmolality rules out DI at water deprivation

NI DI adh production is fine kidney just can’t respond

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12
Q

SIADH management?

A

treat cause

immediate fluid restriction for the hyponatraemia

oral demeclocycline Iv vaptans

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13
Q

In PDR ?

A

In PDR, new blood vessels can be found on the retina or optic disc.

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14
Q

prolactinoma

A

dopamine receptor agonist
bromocripotine
cabergoline

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15
Q

why do prolactinoma present with amenorrhoea

A

suppress GnRh pulsatility

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16
Q

Zona glomerulosa produces?

GFR
ACA

A

aldosterone

fasciculata - Cortisol

Reticularis - androgens

17
Q

investigations for cushing ? - cortisol

A

24 hour urinary cortisol collection

low dose dexa suppression

mri pituitary

18
Q

meiningococcal septiciaemia can cause addissons

A

waterhouse friderichsen syndrome

adrenal haemorrhage from meningitis