endo Flashcards
T2DM management
what is target for metformin only or jst lifestyle?
48
what drug class has an increased risk of a hypoglycaemic episode ?
sulfonylureas - gliclazide
Pioglitazone is what type of drug?
what is the main drawback when is it contraindicated?
Thiazolidinediones
weight gain
cholesterol problems or obese patient
what anti diabetes drug causes UTI as a main side effect ?
SGLT2 inhibitors?
Dapagliflozin
in patients with a high CVD risk what anti diabetic drug is good?
SGL2 inhibitors which cause weight loss
sitagliptin is what type of drug?
Dpp4 inhibitor anti diabetic
weight neutral
works on incretin - blocks the enzyme that breaks down incretin so incretin levels go up in the body
why do certain anti diabetic drugs work on incretin?
incretin increases amount of insulin in body
sitagliptan what drug?
gliclazide
sulphonylureas
pioglitazone
thiazolidinediones
thia zola deen diones
weight gain contraindicated in CVD
works on adipocytes
sitagliptin
dpp4 inhibitor
increases incretin
by blocking enzyme which breaks it down- so more [incretin]
dapagliflozin
sglt2 inhibitor
increases glycosuria
uti / genital yeast conditions
what is the blood glucose target for T1DM pt on waking up?
5-7 mmol/l on waking and
what is the blood glucose target for T1DM before meals?
4-7 mmol/l before meals at other times of the day
types of insulin in t1dm treatment?
offer rapid‑acting insulin analogues injected before meals, rather than rapid‑acting soluble human or animal insulins, for mealtime insulin replacement for adults with type 1 diabetes
ffer multiple daily injection basal–bolus insulin regimens, rather than twice‑daily mixed insulin regimens, as the insulin injection regimen of choice for all adults
twice‑daily insulin detemir is the regime of choice. Once-daily insulin glargine or insulin detemir is an alternative
