haematology 1 Flashcards
what are the functions of the blood
- deliver nutrients to tissue
- removal of waste products
- transports - oxygen, carbon dioxide, hormones, heat
- regulates body fluid, pH, temperature and cell water content
- protects against excess loss by clotting and infection
what are the bloods components
cells - RBC,WBC and platelets and soluble factors eg. proteins and gases
plasma - add anticoagulant, centrifuge immediately and forms Buffy coat
serum - allow clot to form, more efficiently remove RBC
that is the scientific name for red blood cells
erythrocytes
what is the scientific name for white blood cells
leukocytes
what is the scientific name for platlets
thrombocytes
what is a factor
protein
what is the key fact about lymphocytes
- long lived - years
what is the scientific name for blood cell production
haematopoiesis
what cells differentiate into blood cells
pluripotent stem cells
what is the scientific name for the production of red blood cells
erythropoiesis
where do red blood cells originate from
myeloid stem cells
how are red blood cells formed
1) proerthrocytes ejects the nucleus to form reticulocytes ( immature RBC)
2) biconcave discs
where does erythropoiesis occur
bone marrow red pulp
how long to red blood cells live and how are dead ones removed
120 days
removed by spleen and liver
what happens when low O2 concentration is low
1) sensed by the kidneys which releases erthripoietin
2) stimulates differentiation of HSC to be converted into reticulocytes
