HACEK Flashcards
Gram-negative, small, non-motile
HACEK (AACEK) GROUP
- Slow and progressive bacterial endocarditis
(vegetation of fibrinous clots in heart valves). - Utilize d-aminolevulinic acid
HACEK (AACEK) GROUP
Part of indigenous oral microbiota and are
considered as opportunistic pathogens
HACEK (AACEK) GROUP
Fastidious and most of the species grow slowly
(dysgonic) on BAP and CAP and require _____ days of incubation
7 to 14 days
“foam-loving bacteria
AGGREGATIBACTER APHROPHILUS
- Formerly known as H. aphrophilus
- Greek: aphros and philos, “foam-loving”
AGGREGATIBACTER APHROPHILUS
Most common species that causes
EndocarditiS
AGGREGATIBACTER APHROPHILUS
- Isolated from dental plaques and gingival
scrapings - Culture: CAP, raised, convex, granular and
yellowish
AGGREGATIBACTER APHROPHILUS
Formerly known as Actinobacillus
actinomycetemcomitans
Aggregatibacter actinomycetemcomitans
Only catalase positive in HACEK; urease
negative
Aggregatibacter actinomycetemcomitans
collagenase and leukotoxin
virulence factor of Aggregatibacter actinomycetemcomitans
“star-shaped appearance
Aggregatibacter actinomycetemcomitans colonies
A, B, C, D, E and F
Serotypes of Aggregatibacter actinomycetemcomitans
Common cause of periodontitis
AGGREGATIBACTER
ACTINOMYCETEMCOMITANS
Infects the Aortic valve than other ”false-gram
positive” in some parts of the cells
CARDIOBACTERIUM HOMINIS
The only indole-positive HACEK member;
indole positive
CARDIOBACTERIUM HOMINIS
capnophilic and may exhibit “pitting
BAP of CARDIOBACTERIUM HOMINIS
“rosette formation (flower like
appearance) and appear filamentous
Yeast extract on CARDIOBACTERIUM HOMINIS
- Least common isolate
- Assacharolytic like the species of genus
Moraxella
EIKENELLA CORRODENS
“CORRODING BACILLI”
Infections from human bites or clenched fist
injuries.
EIKENELLA CORRODENS
“CORRODING BACILLI”
exhibit a yellow color; pit or corrode the
agar; and have a “sharp bleach” odor
EIKENELLA CORRODENS
“CORRODING BACILLI”
- LDC:(+)
- Arginine dihydrolase: (-)
Biochemical testing of EIKENELLA CORRODENS
“CORRODING BACILLI”
Tendency to resist decolorization
KINGELLA SP.
isolated from degenerative joint and
bone infections (osteoarthritis) in children
younger than 3 years old.
K. kingae
