HA 2 Flashcards
What is needed to diagnose a sinus HA?
Acute sinusitis:
- Purulent nasal d/c
- Pathological sinus findings on imaging
True or false: chronic sinusitis is a cause of sinus HA
False–does not count for diagnosis unless progresses into an acute episode
Activation of the TNC results in what?
Activation of cranial PNS nerves extending into the sinus cavities and tear ducts
True or false: sinus pressure and symptoms are not usually associated with migraines
False
What is the most common HA that is seen by the neurologist?
Migraines
What is the acute treatment for migraines?
- NSAIDs
- Triptans
- Dihydroergotamine (DHE)
What is the rescue therapy for migraines HAs?
Steroids PO
What is the MOA of triptans?
5HT agonists to selectively constrict the meningeal arteries by blocking the release of vasoactive peptides
What are the FDA approved drugs for migraine prevention? (3)
- Topiramate
- Timolol
- Propranolol
What is the use of botulinum toxin in treating migraines?
Prophylactically for chronic migraine suffers
What is the “indication” for butterbur? Side effects?
- Migraines
- Liver toxicity
What are the supplements for migraine prophylaxis?
- Mg supplementation
- High dose B2
True or false: gabapentin is only used for acute attacks of migraines
False–prophylactically
What is the diuretic that may help with migraine prophylaxis?
Candesartan
What type of antidepressants are used for migraines?
TCAs
What are the three major TCAs?
- Amitriptyline
- Nortriptyline
- Imipramine
The use of abortive treatments for migraines should be limited to how many times per week? Why?
2
Avoid the development of rebound HAs
What may happen with numerous, untreated migraines?
Increase in frequency, duration, and severity d/t changes in pain generators
How long does it take for migraine prophylaxis to be effective?
8-12 weeks
What is the pathophysiology of Trigeminal Autonomic Cephalgias (TACs)?
Activation of the trigeminal autonomic reflex that causes “allergy” symptoms on the side of the reflex
What are the characteristics of cluster HAs?
Piercing, unilateral stabbing pain, accompanied by ipsilateral lacrimation and nasal congestion
Which gender is usually affected with cluster HAs?
Males
How often do cluster HAs recur? When in the day do they usually occur?
1-10 attacks per day, usually at night
How long do episodes of cluster HAs happen?
30-120 minutes
What is the seasonal pattern of cluster HAs?
usually in the fall and spring