gut-brain axis Flashcards

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1
Q

function of gut brain axis

A
  • bidirectional multi-faceted communication link between central and enteric nervous system
  • involves direct and indirect pathways between cognitive and emotional areas in the brain within the GI tract
    -chronic stress is heavily links to disruptions within the GI tract
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2
Q

other things that the GBA impact

A

impact immunity and neurotransmitter production
- better diversity better production and immunity

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3
Q

gut microbiota

A
  • different types of bacteria and other microorganisms within the gastrointestinal system
  • if there is a disturbance in the gut then it can affect the gut brain axis
  • can influence, production of serotonin and other neurotransmitters within the gut
  • agents produced can go through the bloodstream
  • each individual has their own personal compisiton of gut microbiota
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4
Q

define enterotype

A

referred to the unique combination of gut microbiota we each possess

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5
Q

define microbiome

A

collective term population of microbiota in a defined environment
- not fixed and can be affect by internal and external factors and diminishes with age

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6
Q

healthy gut microbiota

A

high levels of microbiota richness, diversity, stable, resilient and resistance and recover a stable state

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7
Q

define gut bysbiosis

A

referred to an unbalanced gut microbiome, either in number or type of microbiota

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8
Q

disturbances in gut microbiota

A
  • changes in the production of neurotransmitters within the gut
    -production and activity of neurotransmitters in the NS
  • immune system impairments
  • digestive disorders
  • stress reactivity
  • numerous inflammatory diseases and infections
  • heart disease
  • mood and cognitive functioning
  • neurological conditions
  • various mental health disorders
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9
Q

link with stress

A

stress can disturb the GBA, gut microbiome and the develepment of gastrointestinal disorders.

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10
Q

impact the gut microbiota in humans

A
  • researchers found that infants born to mothers who are highly stressed during pregnancy tended to have abnormal composition of gut microbiota
  • infants have higher levels of harmful bacteria and lower levels of beneficial bacteria, infants had significantly higher levels of stress related gastrointestinal symptoms
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11
Q

how stress influence the gut microbiota

A
  • stress can affect different physiological functions of GI tract such as
  • changes in blood
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12
Q

stress and gut

A

researches have said that if you have a healthy gut it minimised stress and if you ahve reduced stress then you have a healthy gut

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13
Q

vagus nerve

A

it allows for the connection from the brain to your brain via the afferent pathway

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14
Q

where is serotonin produced

A

90% produced in it in the gut

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15
Q

impact of antibiotics

A

decreases immune system and thus when they experience a stressor , they are more vulnerable to develop a disease

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16
Q

stress affecting physiological functions of gatrointestinal traact

A
  • changes in blood flow
    gastric secretion and gut motility
    increase in visceral perception
    negative effects on gut microbiota
17
Q

efferent : brain to gut

A

10%

18
Q

afferent; gut to brain

A

90%

19
Q
A