gut-brain axis Flashcards
function of gut brain axis
- bidirectional multi-faceted communication link between central and enteric nervous system
- involves direct and indirect pathways between cognitive and emotional areas in the brain within the GI tract
-chronic stress is heavily links to disruptions within the GI tract
other things that the GBA impact
impact immunity and neurotransmitter production
- better diversity better production and immunity
gut microbiota
- different types of bacteria and other microorganisms within the gastrointestinal system
- if there is a disturbance in the gut then it can affect the gut brain axis
- can influence, production of serotonin and other neurotransmitters within the gut
- agents produced can go through the bloodstream
- each individual has their own personal compisiton of gut microbiota
define enterotype
referred to the unique combination of gut microbiota we each possess
define microbiome
collective term population of microbiota in a defined environment
- not fixed and can be affect by internal and external factors and diminishes with age
healthy gut microbiota
high levels of microbiota richness, diversity, stable, resilient and resistance and recover a stable state
define gut bysbiosis
referred to an unbalanced gut microbiome, either in number or type of microbiota
disturbances in gut microbiota
- changes in the production of neurotransmitters within the gut
-production and activity of neurotransmitters in the NS - immune system impairments
- digestive disorders
- stress reactivity
- numerous inflammatory diseases and infections
- heart disease
- mood and cognitive functioning
- neurological conditions
- various mental health disorders
link with stress
stress can disturb the GBA, gut microbiome and the develepment of gastrointestinal disorders.
impact the gut microbiota in humans
- researchers found that infants born to mothers who are highly stressed during pregnancy tended to have abnormal composition of gut microbiota
- infants have higher levels of harmful bacteria and lower levels of beneficial bacteria, infants had significantly higher levels of stress related gastrointestinal symptoms
how stress influence the gut microbiota
- stress can affect different physiological functions of GI tract such as
- changes in blood
stress and gut
researches have said that if you have a healthy gut it minimised stress and if you ahve reduced stress then you have a healthy gut
vagus nerve
it allows for the connection from the brain to your brain via the afferent pathway
where is serotonin produced
90% produced in it in the gut
impact of antibiotics
decreases immune system and thus when they experience a stressor , they are more vulnerable to develop a disease