GU Geriatrics Flashcards
where does prostate hyperplasia typically occur in BPH
periurethral or transitional zone
sx BPH
irritative sx - frequency, urgency, nocturia, incontinence
obstructive sx - weak flow, incomplete emptying
DRE - uniform, enlarged, smooth, firm, contender, rubbery prostate
tx BPH
observe - lifestyle
alpha-1 blockers - best initial but don’t change prostate size (tamsulosin – other zosins)
5-alpha reductase inhibitors - reduces size of prostate (finasteride and dutasteride)
TURP
what is paraphimosis
retracted foreskin in an uncircumcised male that cannot be returned to normal
EMERGENCY
tx paraphimosis
manual reduction
granulated sugar, injection o hyaluronidase
incision or circumcision= definitive
what is phimosis
inability to retract foreskin over glans
tx phimosis
proper hygiene and stretching of skin
4-8 weeks of topical steroids
circumcision = definitive
MC population affected by urge incontinence
older women
pathophys of urge incontinence
detrusor muscle overactivity
another name for urge incontinence
overactive bladder
tx urge incontinence
bladder training !!!!!
lifestyle + Kegel
beta-3 agonists - mirabegron, vibegron
antimuscarinic drugs - trospium, darifenacin, tolterodine
botox injections
overflow incontinence is caused by either ____ or ____
bladder detrusor muscle under activity or bladder outlet obstruction (like BPH)
dx overflow incontinence
clinical
PVR > 200
tx overflow incontinence
intermittent or indwelling catheter
cholinergic (Bethanechol)
MC bacterial cause of cystitis
E coli
dx cystitis
UA - pyuria (>10 WBCs/hpf)
Urine culture - definitive - needs to be clean catch
tx cystitis
1st line - nitrofurantoin, TMP-SMX, or fosfomycin
2nd line - fluroquinolones
phenazopyridine is a bladder analgesic (turns fluids orange)
MC bacterial cause of pyelo
E coli
dx pyelo
UA - pyuria (> 10 WBCs/hpf); WBC casts are hallmark
Urine culture - definitive
tx pyelo
fluoroquinolones - cipro or levo
MCC prostatitis
> 35 E coli
< 35 chlamydia and gonorrhea
sx prostatitis
spiking fever, chills, perineal pain
recurrent UTIs
PE prostatitis
boggy and exquisitely tender prostate - acute
nontender, boggy prostate - chronic
dx prostatitis
UA and urine culture - pyuria and bacteriuria
what should be avoided in prostatitis
prostatic massage
tx prostatitis
> 35 - fluoroquinolones
< 35 - doxy + cef
tx for 4-6 weeks
MC type of bladder CA
urothelial (transitional cell)
MC risk for bladder CA
tobacco smoking
sx bladder CA
hematuria - gross, painless
dx bladder CA
UA to rule out benign
cystoscopy
renal function tests
CT urography
cystoscopy with bx - criterion standard
tx bladder CA
TURP
radical cystectomy if invading muscle
metastatic - platinum-based chemo
MC type prostate CA
adenocarcinoma
RF prostate CA
increasing age
black
genetics
sx prostate CA
asx - most
urinary sx
back or bone pain
PE prostate CA
hard, indurated, nodular, enlarged, asymmetrical prostate
most accurate test for prostate CA
transrectal US-guided needle biopsy
what grading scale for prostate CA
Gleason grading system
tx prostate CA
GnRH agonist - Leuprolide, Goserelin
GnRH antagonist - Degarelix, Relugolix
prostatectomy