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Exam 9 > Gruetter > Flashcards

Gruetter Flashcards

1
Q

Verapamil and diltiazem

A

Ca channel blockers - nondihydropyridines

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2
Q

Minoxidil

A

K channel activators

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3
Q

Nitroprusside, nitroglycerin, isosorbide dinitrate,NO, hyralazine

A

Guanylate cyclase activators

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4
Q

Fenoldopam

A

Dopamine D1 receptor agonists

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5
Q

Sildenafil, tadalafil

A

PDE inhibitor

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6
Q

Lisinopril, Enlapril

A

ACEi

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7
Q

Losartan, valsartan

A

AT2 receptor inhibitor

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8
Q

Aliskrein

A

Renin inhibitor

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9
Q

Arterial dilation decreases

A

AFterload, TPR

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10
Q

Venous dilation decreases

A

CO and venous return

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11
Q

Dihydropyridines (amilodipine) mainly causes vasodilation of _________ by decreasing influx of Ca via __________ Ca channels

A

Arteries

L-type

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12
Q

In heart, L type Ca channels mainly inhibited by

A

Verapamil

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13
Q

Verapamil inhibits phase ____________ of AP in muscle, to decrease Ca entry and decrease contractility

A

2 (plateau)

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14
Q

Verapamil inhibits phase ________ of AP in SA and AV nodes. Decrease firing of SA node to decrease HR. Decrease conduction of AV to cause AV block.

A

0 (depolarization)

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15
Q

Dihydropyridines (Amlodipine) mainly cause

A

Vasodilation

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16
Q

Verapamil (nondihydropyridines) mostly affects

A

Heart

17
Q

All Ca channel blockers have __________ metabolism

A

Hepatic

18
Q

_____ can be used for chronic stable and variant angina, hypertension

A

All ca channel blockers

19
Q

____ can be used for supraventricular tachyarrhythmias and to terminate paroxysmal supraventricular tachycardia

A

Verapamil

20
Q

Increased risk of mortality and MI with _____________

A

Short acting dihydropyridine a

21
Q

Amlodipine

A

Ca channel blocker - dihydropyridine

22
Q

Adversely cause hypotension, edema, and headaches

A

Dihydropyridines ca channel blockers

23
Q

Adversely causes edema

A

Diltiazem

24
Q

Adversely causes hypotension, CHF, AV block, headaches, and constipation

A

Verapamil

25
Q

Avoid giving _____ if pt already has CHF or AV block

A

Verapamil

26
Q

Avoid ______ if pt already has hypotension or severe hepatic disease

A

All ca channel blockers

27
Q

Can interact with CYP3A4 drugs, concurrent beta blockers, and digoxin

A

Ca channel blockers

28
Q

Increased efflux of K will ______ the cell causing ___________ TPR

A

Hyperpolarize

Decreased

Exam 9 (12 decks)

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