Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Exam 9 > Antiarrhythimics > Flashcards

Antiarrhythimics Flashcards

1
Q 
Decreased automaticity
Restoration of conduction (restore depressed conduction and reverse re-entry) 
Decreased conduction (Covert 1-way to 2-way block and block re-entry) 
Decreased/Increased ERPs (reverse or block re-entry)
Homogeneity of ERPs
A

Antiarrhythmics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Most arrhythmias caused by

A

Abnormal conduction pathway

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Class ___ drugs good at increasing ERP

A

3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Class _____ drugs good at decreasing conduction velocity

A

1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Na channel blockers - slow conduction

A

Class 1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Beta-receptor blockers

Inhibit sympathetic input to AV node

A

Class 2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Prolong APD

Increase ERP

A

Class 3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Ca channel block

A

Class 4 drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Class one drugs bind to Na channels in their ______ state and dissociate in their _____ closed

A

Open

Closed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Class 1A
Class 1B
Class 1C

A

Moderate dissociation
Fast dissociation
Slow dissociation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Good for tachycardia, hypoxia, ischemia

A

Class 1B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

A lot of drug stays bound from one AP to next. Most profound effect on slowing conduction

A

Class 1C

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Associate during

Dissociation during

A

Systole

Diastole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Procainamide is a class _____ drug

A

1A

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Decrease automaticity
Decrease conduction velocity
Increase APD and ERP

A

Procainamide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Has some Anticholinergic effects

A

Procainamide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Has unpredictable effects on the AV node

A

Class 1A

Procainamide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Directly will decrease AV node conduction
Anticholinergic effects increase AV node conduction
Increase/Decrease AV node conduction

A

Procainamide

Class 1A

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Avoid in prolonged QT syndrome because can cause torsades de pointes

A

Procainamide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Used for life threatening ventricular arrhythmias
Orally and IV
Hepatic and renal metabolism

A

Procainamide

Class 1A

21
Q

Has active metabolite NAPA

A

Procainamide

22
Q

Causes ANA formation and a lupus like syndrome

A

Procainamide (Class 1A)

Hydralazine

23
Q

Causes agranulocytosis and leukopenia early in treatment

A

Procainamide

24
Q

Has proarrhythmic effects

A

Procainamide

25
Q

Avoid in prolonged QT, lupus, and hypokalemia

A

Procainamide (Class 1A)

26
Q

Lidocaine and mixiletine

A

Class 1B drugs

27
Q

Have minimal effects in normal myocardium, and class 1A like action in diseased myocardium

A

Class 1B drugs

28
Q

Use in life threatening ventricular arrhythmias and digoxin-induced arrhythmias

A

Lidocaine

29
Q

Hepatic metabolism- first pass elimination
IV only
Must decrease dose in liver disease & CHF

A

Lidocaine

30
Q

Can cause seizures with CNS

A

Lidocaine

31
Q

Has hypersensitivity to other amides, causes severe hepatic dysfunction

A

Lidocaine

32
Q

Similar to lidocaine
Orally effective
Causes GI, CNS, tremors, and thrombocytopenia

A

Mexiletene (Class 1B)

33
Q

Flecainide and Propafenone

A

Class 1C drugs

34
Q

Markedly slow conduction, decrease automaticity

A

Flecainide and Propafenone

35
Q

Used in life threatening ventricular arrhythmias and disabling supra ventricular arrhythmias IN the ABSENCE of organic heart disease

A

Flecainide (Class 1C)

36
Q

Increases mortality post MI

Avoid in pre-existing heart probes

A

Flecainide (Class 1C)

37
Q

Conduction block

A

Flecainide

38
Q

Similar to Flecainide

A

Propafenone

39
Q

Inhibit sympathetic input (Decreases automaticity and conduction velocity, increases refractories)
Prominent effects in SA and AV nodes
Decrease contractility

A

Class 2 beta blockers

40
Q

Used in supraventricular arrhythmias, a flutter and a fib, symptomatic PVCs, post MI, and CHF

A

Class 2 (beta blockers)

41
Q

Can cause bronchoconstriction, CHF, AV block, cold extremities
Increase insulin-induced hypoglycemia b/c they block the reflexive increase in HR

A

Class 2 beta blockers

42
Q

Propanolol is

A

Nonspecific beta blocker

43
Q

Metoprolol is

A

Cardioselective beta blocker

44
Q

Esmolol is

A

Cardio selective beta blocker

45
Q

Short half life (mins). Control ventricle rate in Afib and a flutter. Control sinus tachycardia

A

Esmolol

46
Q

Homogenous prolongation of APD (proarrhythmic).

A

Class 3

47
Q

Treat refractory life threatening ventricular arrhythmias

A

Class 3

48
Q

Increased automaticity
Conduction block or slowing
Decreased/Increased ERPs
Heterogeneity of ERPs

A

Proarrhythmics

Exam 9 (12 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions