Gruetter 3

Question 1

Decrease aldosterone secretion, decrease angiotensin 2 mediated vasoconstriction and CV remodeling, and inhibit breakdown of bradykinin causing increased prostaglandins

Answer 1

ACEi

Question 2

Decrease TPR, BP, and Na and fluid retention

Answer 2

ACEi

Question 3

Used for hypertension, CHF, post MI, and to prevent diabetic nephropathy

Answer 3

ACEi

Question 4

Adversely - fetopathic potential, cough, and hyperkalemia

Answer 4

ACEi

Question 5

Avoid in pregnancy, K supplements, and hypersensitivity

Answer 5

ACEi

Question 6

Competitive antagonist at AT1 receptors

Answer 6

ARBs

Question 7

Similar to ACEi but less cough.

Still cause fetopathic potential and hyperkalemia

Answer 7

ARBs

Question 8

Avoid in pregnancy, BL renal vascular stenosis, K supplements, and hypersensitivity

Answer 8

ARBs and renin inhibitors (Aliskrein)

Question 9

Also decrease aldosterone, remodeling

Answer 9

ARBs

Question 10

Inhibition of renin will decrease

Answer 10

Angiotensin 2

Question 11

Similar to ACEi but less cough. Still have fetopathic potential and hyperkalemia. use in hypertension

Answer 11

Renin inhibitors

Question 12

ACE inhibition will _______ angiotensin 2

Answer 12

Decrease