gram negative bacilli (enterobacterales) Flashcards
enterobacterales characteristics (5)
- found in colon
- oxidase negative
- ferments glucose
- cell wall: somatic O antigen and flagellar H antigen
- macconkey agar: fermenting or non-fermenting
lactose fermenting enterobacterales (2)
- e. coli
- klebsiella
non-lactose fermenting enterobacterales (3)
- salmonella
- shigella
- proteus
escherichia coli virulent strains (4)
- EHEC (enterohaemorrhagic e coli)
- VTEC (verocytotoxin-producing e coli)
- STEC (shiga-like toxin e coli)
- ETEC (enterotoxic e coli)
escherichia coli clinical presentations (4)
- commonest cause of UTI
- neonatal septicaemia, meningitis (vertical transmission)
- diarrhoeal disease (by virulent strains)
- shiga-LIKE toxin is absorbed, spread through bloodstream–> Haemolytic Uraemic Syndrome–> renal failure/death
escherichia coli transmission
faecal-oral (normal gut flora)
escherichia coli treatment (3)
- ceftriaxone (not for ESBL strains)
- carbapenems
- ciprofloxacin
HYDRATION!!!!!
klebsiella clinical presentations (3)
- common cause of community & nosocomial UTI
- friedlander’s pneumonia (severe community acquired bronchopneumonia w abscess)
- nosocomial infections (mostly by ESBL strains)
klebsiella pneumonia transmission (2)
- droplets
- faecal-oral
klebsiella pneumonia treatment (3)
- ceftriaxone (not for ESBL strains)
- carbapenems
- ciprofloxacin
HYDRATION!!!!!
enteric/typhoidal salmonella (S. typhi, S. paratyphi) transmission
faecal-oral
enteric/typhoidal salmonella (S. typhi, S. paratyphi) clinical presentations (2)
- typhoid fever (rose spots, slowly rising fever)
- ulceration & perforations of peyer’s patches (due to infected bile from gallbladder)
enteric/typhoidal salmonella (S. typhi, S. paratyphi) treatment (2)
- ceftriaxone
- ciprofloxacin
non-typhoidal salmonella transmission
foodborne (poorly cooked poultry/eggs, animal faecal contamination)
non-typhoidal salmonella clinical presentations (2)
- gastroenteritis/food poisoning
- bacteremia (causes invasive infections)
- UTI