gram neg cocci (neisseria)

Question 1

overview

Answer 1

gram negative diplococci
oxidase positive
chocolate agar (inactive blood agar)
VPN agar (vancomyocin, polymyxin, nystatin) Thayer agar

MAC- (complement C5-C9 deficiency cant fom MAC attack comples so they have increased infections of neisseria)

Virulence factors: pillus- genetic rearrangement (antigenic variation), IgA protease

both ferment glucose

Question 2

n. meningidits

Answer 2

College dorm room
respiratory droplets often in colleges
ferments maltose
encAPSULATED  (vaccines are the capsule)
Type B does not have a vaccine (ACD have vaccine capsule)

naso pharynx as the mode of transmission then transmitted via respiratory secretion

Patients with sickle cell disease are at risk because of autsplenectomy. Lipo oligosaccharides envelopes in blood cause a massive inflammatory response, increasing permeability of blood vessels, causing leaky capillaries, and a petechia rash (disseminated vascular thromocytopenia)

hypovolemia and shock–> adrenal insufficiency->more shock (waterhouse -f syndrome)

3rd generation of cephalasporin (Ceftriaxone bc its gotta pass thru the BBB)- need close contact profolactic rifampin

Question 3

N. gonorrhoeae

Answer 3

gonzoz Bar scene

STI
gram negative diplococci, that infect PMN, facultative intracellular. Not encapsulated. Genitalia of men and women that can go up GU system in men.

In women-> pelvic inflammatory disease (PID -causes scarring that could lead to infirtility) with white pirulent discharge thick white hot wax that can spread in the peritineum (Fitz-hue syndrome-> violin adhesions in capillaries of liver

Poly arthritis (in one knee typically), pregnant women can pass the disease to baby (neonatal conjuctivitis usually one week after birth)

Treatment: ceftriazone (usually coinfected with chlamydia- so you need a macrolide like azythromycin or )