Gout Flashcards
1
Q
Gout
A
Type of inflammatory arthritis
Excess of uric acid and its salts (rates) to accumulate in the blood-stream and the joints respectively.
2
Q
Gout Aetiology
A
Deposition of monosodium urate crystals
- needle shaped
- Negatively birefringent
High uric acid levels
- Increased protein intake
- Increased cell breakdown
- Renal under excretion
- Diuretics
- Renal failure
- Excessive alcohol intake
- Diet
3
Q
Gout Symptoms
A
Intensely painful Red, hot, swollen May mimic septic arthritis Rapid Onset Gouty tophi (painless white accumulations which can occur in soft tissues and occasionally erupt through the skin)
4
Q
Gout Investigations
A
Joint Aspiration
Serum Urate >7mg/dL
5
Q
Gout Common Sites
A
Any site
1st MTP Joint
- Podagra
Ankle joint
Knee joint
6
Q
Gout Triggers
A
Dehydration
Trauma
Surgery
7
Q
Gout Treatment
A
Acute
- NSAIDs
- Corticosteroids
- Opioid analgesia
- Colchicine (if NSAID intolerant)
Chronic
- Allopurinol
- Febuxostat
8
Q
Pseudogout
A
Joint pain and swelling, resembling gout, caused by crystals of calcium pyrophosphate synovial membrane and fluid
9
Q
Pseudogout aetiology
A
Calcium pyrophosphate dehydrate crystal deposition
- Rhomboid Shaped
10
Q
Pseudogout Common Sites
A
Knee
Wrist
Ankle
11
Q
Pseudogout Associations
A
Hyperparathyroidism Hypothyroidism Renal osteodystrophy Haemochromatosis Wilson's disease
