Glycolysis Flashcards
Define glycolysis
Splitting glucose to pyruvate to extract energy
Anaerobic process
Occurs in the cytoplasm
What are the overall products of glycolysis?
2 pyruvate molecules
2 ATP molecules
2 NADH
What controls the rate of glycolysis?
Phosphofructokinase
What occurs in step 1?
Glucose converted to glucose-6-phosphate
By hexokinase
ATP molecule converted to ADP
What occurs in step 2?
Glucose-6-phosphase converted to frucotse-6-phosphate
By phosphoglcuose isomerase
What occurs in step 3?
Fructose-6-phosphate converted to fructose-1,6-bisphosphate
By phosphofructokinase
ATP converted to ADP
What occurs in step 4?
Fructose-1,6-bisphosphate converted to dihydroxyacetone phosphate and glyceraldehyde-3-phosphate
What occurs in step 5?
Dehydroxyacetone phosphate is converted to glyceraldehyde-3-phosphate by triode phosphate isomerase
What occurs in step 6?
Glyceraldehyde-3-phosphate is converted to 1,3-bisphosphoglycerate
By glyceraldehyde-3-phosphate dehydrogenase
Inorganic phosphate and NAD+ become H+ and NADH
What occurs in step 7?
1,3-biphosphoglycerate is converted to 3-phosphoglycerate
By phosphoglycerate kinase
ADP converted to ATP
What occurs in step 8?
3-phosphoglycerate converted to 2-phosphoglycerate
By phosphoglycerate mutase
What occurs in step 9?
2-phosphoglycerate is converted to phosphoenolpyruvate
By enolase
H2O lost
What occurs in step 10?
Phosphoenolpyruvate converted to pyruvate
By pyruvate kinase
ADP converted to ATP
What happens in anaerobic respiration?
Glucose converte to pyruvate and then to lactate
2 ATP produced
NAD+ and NADH recycled
What are the consequences of anaerobic respiration?
Increased lactate production
pH falls
Muscle pain
