Glycolysis Flashcards
Kinase
Phosphorylation
Substrate level phosphorylation
Mutase/Isomerase
Make isomer
Dehydrogenase
Redox reaction:
- oxidative phosphorylation (glycolysis)
- oxidation
- oxydative decarboxylation
MAKE NADH
Step 1
Glucose (C6H12O6)
ATP -> ADP
phosphorylation
hexokinase
Glucose-6-phosphate (C6H11O6P)
Step 2
Glucose-6-phosphate (C6H11O6P)
isomerisation
phosphoglucomutase
Fructose-6-phosphate (C6H11O6P)
Step 3
Fructose-6-phosphate (C6H11O6P)
ATP -> ADP
phosphorylation
phosphofructokinase
Fructose-1,6-diphosphate (C6H10O6P2)
Step 4
Fructose-1,6-diphosphate (C6H10O6P2)
cleavage
aldolase
1) 3-Phosphoglyceraldehyde (PGAL) (C3H5O3P)
2) Dihydroxyacetone phosphate (C3H5O3P)
Step 5
Dihydroxyacetone phosphate (C3H5O3P)
isomerisation
tri phosphate isomerase
3-Phosphoglyceraldehyde (PGAL) (C3H5O3P)
Step 6
3-Phosphoglyceraldehyde (PGAL) (C3H5O3P)
input: H3PO4 or P
NAD+ -> NADH + H+
oxidative phosphorylation
glyceraldehyde phosphate dehydrogenase
1,3-Diphosphoglycerate (C3H4O3P2)
Step 7
1,3-Diphosphoglycerate (C3H4O3P2)
ADP -> ATP
substrate level phosphorylation (SLP)
diphosphoglycerate kinase
3-Phosphoglycerate (C3H5O4P)
Step 8
3-Phosphoglycerate (C3H5O4P)
isomerisation
phosphoglyceromutase
2-Phosphoglycerate (2PGA) (C3H5O4P)
Step 9
2-Phosphoglycerate (2PGA) (C3H5O4P)
-H2O
dehydration
enolase
Phosphoenol piruvate (C3H3O3P)
Step 10
Phosphoenol piruvate (C3H3O3P)
ADP -> ATP
substrate level phosphorylation (SLP)
piruvate phosphokinase
Piruvic acid (C3H4O3)