Gluconeogenesis Flashcards
_____ catalyzes the conversion of Fructose-1, 6 bisP to Fructose-6-P
Fructose 1,6 bisphosphatase
______ catalyzes the conversion of glucose-6-p to glucose
Glucose 6-phosphatase
Under fasting condition, pyruvate dehydrogenase is phosphorylated to its inactive form, therefore ____ is not converted to _____
Pyruvate
Acetyl-coA
Acety-coA, which is produced by oxidation of ______, activates ____
Fatty acid
Pyruvate carboxylase
High level of ____ inhibits pyruvate dehydrogenase and activates ____
Acetyl-coA
Pyruvate carboxylase
Oxaloacetate produce PEP in a reaction catalyzes by _____
PEP carboxylase
When glucagon level is elevated, liver pyruvate kinase is _____ and inactivated by a mechanism that involves ___
Phosphorylated
cAMP
Insulin activates the phosphatase that _____ glycogen synthase and ____ glycogen phosphorylase
Activates
Inhibit
Insulin promotes the synthesis of the_____ that are released from the liver into the blood as ____
triacylglycerols
VLDL
Insulin stimulates the transport of glucose into ____ and _____
Muscle
Adipose tissue
Under fasting condition, fatty acid and glycerol are released from triacylglycerols store of _____, fatty acid travel to the ____ where thy undergo beta oxidation
Adipose tissue
Liver
Pyruvate carboxylase requires ____ as cofactor
Biotin
