Fatty Acid Oxidation Flashcards

0
Q

Long-chained fatty acid are ______ , they can disrupt the _____ bonding between amino acid side chain I protein

A

Hydrophobic

Hydrophobic

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1
Q

Fatty acids are released from the _____ of adipose tissue by ____ into the blood

A

Triacylglycerol

Lipase

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2
Q

Long chain fatty acid are transported in the blood by binding to _____

A

Albumin

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3
Q

in the liver, ketone bodies are synthesized in the mitochondrial matrix from _____ generated from _______

A

Acetyl-coA

Fatty acid oxidation

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4
Q

Ketongenic amino acid such as ____ can be catabolized into ____ or _____ to make ketone bodies

A

Leucine isoleucine Lysine
Acetyl-coA
Acetoacetyl-coA

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5
Q

Ketone bodies can be oxidized as fuel in all tissues except ____ and ____

A

Liver

Red blood cells

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6
Q

Beta oxidation generates

A

Acteycoa
NADH
FADH2

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7
Q

_____ activates fatty acid to fatty acyl-coA

A

Fatty acyl-coA synthetase

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8
Q

Oxidation of 1 mol of palmitate yields _____ acetyl coA

A

8

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9
Q

Oxidation of 1 mol of palmitate yields net _____ ATP, __ ATP per NADH, ___ ATP per FADH2

A

106

  1. 5
  2. 5
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10
Q

In oxidation of of unsaturated fatty acid, isomerase moves double bond can covert them to ___ configuration, reductase reduce double bond utilizing ____

A

Trans

NADPH

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11
Q

Final product of odd chained fatty acid oxidation is _______, which is converted to _____, an snapper optic route for TCA cycle

A

Propionyl coA

Succinyl coA

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12
Q

_____ cannot perform beta oxidation, ___ and ____ do not use fatty acid as a fuel in a significant manner

A

Red blood cells

Brain adipocyte

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13
Q

w-oxidation results in a ____ that is subject to beta oxidation

A

Dicarboxylic acid

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14
Q

The 3 pathway if a, b, and w-oxidation decrease the level of _____ fatty acid and ____ compounds with fatty acid like structure that might be toxic at high concentration

A

Water-insoluble

Xenobiotic

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15
Q

Very long chained fatty acid of 24 to 26 carbons are oxidized exclusively in the ______

A

Peroxisome

16
Q

Branches chained fatty acid in the diet are from _______ and is oxidized in the ____ using combination of a and b-oxidation

A

green vegetables

Peroxisomes

17
Q

Ketone body oxidation occurs in the ____, one ketone body is oxidized into 2 molecules of _____ to enter into TCA cycle

A

Mitochondria matrix

Acetyl-coA

18
Q

Oxidation of 1 acetoacetate generate ___ AtP, oxidation of 1 b-hydroxybutyrate generate ___ ATP

A

19 21.5