Fatty Acid Oxidation Flashcards
Long-chained fatty acid are ______ , they can disrupt the _____ bonding between amino acid side chain I protein
Hydrophobic
Hydrophobic
Fatty acids are released from the _____ of adipose tissue by ____ into the blood
Triacylglycerol
Lipase
Long chain fatty acid are transported in the blood by binding to _____
Albumin
in the liver, ketone bodies are synthesized in the mitochondrial matrix from _____ generated from _______
Acetyl-coA
Fatty acid oxidation
Ketongenic amino acid such as ____ can be catabolized into ____ or _____ to make ketone bodies
Leucine isoleucine Lysine
Acetyl-coA
Acetoacetyl-coA
Ketone bodies can be oxidized as fuel in all tissues except ____ and ____
Liver
Red blood cells
Beta oxidation generates
Acteycoa
NADH
FADH2
_____ activates fatty acid to fatty acyl-coA
Fatty acyl-coA synthetase
Oxidation of 1 mol of palmitate yields _____ acetyl coA
8
Oxidation of 1 mol of palmitate yields net _____ ATP, __ ATP per NADH, ___ ATP per FADH2
106
- 5
- 5
In oxidation of of unsaturated fatty acid, isomerase moves double bond can covert them to ___ configuration, reductase reduce double bond utilizing ____
Trans
NADPH
Final product of odd chained fatty acid oxidation is _______, which is converted to _____, an snapper optic route for TCA cycle
Propionyl coA
Succinyl coA
_____ cannot perform beta oxidation, ___ and ____ do not use fatty acid as a fuel in a significant manner
Red blood cells
Brain adipocyte
w-oxidation results in a ____ that is subject to beta oxidation
Dicarboxylic acid
The 3 pathway if a, b, and w-oxidation decrease the level of _____ fatty acid and ____ compounds with fatty acid like structure that might be toxic at high concentration
Water-insoluble
Xenobiotic
Very long chained fatty acid of 24 to 26 carbons are oxidized exclusively in the ______
Peroxisome
Branches chained fatty acid in the diet are from _______ and is oxidized in the ____ using combination of a and b-oxidation
green vegetables
Peroxisomes
Ketone body oxidation occurs in the ____, one ketone body is oxidized into 2 molecules of _____ to enter into TCA cycle
Mitochondria matrix
Acetyl-coA
Oxidation of 1 acetoacetate generate ___ AtP, oxidation of 1 b-hydroxybutyrate generate ___ ATP
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