Digestion Of Lipid Flashcards
______ are the major fat in the human diet
Triacylglycerols
Triaclyglycerol contain a ____ backbone to which _______ are esterified
Glycerol
3 fatty acid
Lingual and gastric lipase preferentially hydrolyzed dietary TGs that contain ______ fatty acid
Short and medium-chained
TGs are mainly digested in the lumen of intestine by _____
Pancreatic lipase
TGs are hydrolyzed by pancreatic lipase to ____ and _____
Fatty acids
2-monoacylglycerol
The bile salt are ____compound and are synthesized in the ______
Amphipathic
Liver
Dietary fat leaves the stomach and enters the small intestine where it is ______
Emulsified
What process break down fat droplet into fine particles suspending in aqueous solutions?
Emulsification
Dietary fat are emulsified in the small intestine by ______
Bile salts
The contraction of the gallbladder and secretion of pancreatic enzymes are stimulated by the gut hormone _______
Cholecystokinin
______ secrete cholecystokinin when stomach contents enters ____
Intestinal cell
Intestine
Increased acidity in the lumen of small intestine triggers the release of _____ (a peptide hormone)
Secretin
Secretin promotes _____ secretion by the liver, pancreas and certain intestinal cells
Bicarbonate
Bicarbonate increases intestinal pH to roughly ____, which is optimal for action of all digestive enzyme in the intestine
6
Major apoprotein associated with chylomicron is
B48
The apoprotein for VLDL is ____
B-100
___ mainly carry dietary TGs in the blood
Chylomicron
Chylomicron contains ____ and _____
Cholesterol
Fat soluble vitamin
TGs are synthesized in the ______, and apoB-48 is synthesized in the
Smooth ER
Rough ER
Nascent chylomicron enters blood through _____
Thoracic act
Nascent chylomicron receive ___ and ___ from High-density lipoprotein (HDL) to form mature CM
ApoCII
ApoE
Adipocyte isozyme of LPL has a higher Km than the _____ isozymes, therefore, adipose LPL is ____ active after a meal.
Muscle
More
____ activates lipoprotein lipase LPL on capillary endothelial cells within the muscle and adipose tissue
ApoCII
Apoprotein ___ is responsible for uptake of chylomicron remnants
E
