Glucagon Flashcards
1
Q
Presentation
A
1 mg (IU) in 1 ml hypokit
2
Q
Pharmacology
A
Hormone normally secreted by the pancreas
Actions:
- Causes an increase in BGL concentrations by converting stored liver glycogen to glucose
3
Q
Metabolism
A
- Mainly by the liver
- also kidneys and plasma
4
Q
Indications
A
Diabetic hypoglycaemia (BGL <4 mmol/L) in pts with altered GCS and unable to self-administer oral glucose
5
Q
Contras
A
NIL of significance in the above indication
6
Q
Precautions
A
NIL of significance in the above indication
7
Q
Route of administration
A
IM
8
Q
Side effects
A
Nausea and vomiting (rare)
9
Q
Special notes
A
Not all pts will response to glucagon.
Eg: inadequate glycogen stores in the liver (alcoholics/malnourished)
10
Q
IM effects
A
Onset: 5 mins
Peak: n/a
Duration: 25 mins
11
Q
Hypoglycaemia
A
BGL < 4 mmol/L and not responding to commands
- unable to insert IV
- 1 IU IM
- single dose only
