Ceftriaxone Flashcards
1
Q
Presentation
A
1 g sterile powder in a glass vial
2
Q
Pharmacology
A
Cephalosporin antibiotic
3
Q
Metabolism
A
Excreted unchanged in urine (33% - 67%) and in bile
4
Q
Indications
A
- Suspected meningococcal septicaemia
- Severe sepsis (consult only)
5
Q
Contras
A
Allergy to Cephalosporin antibiotics
6
Q
Precautions
A
Allergy to Penicillin antibiotics
7
Q
Route of administration
A
IV (preferred)
IM (if IV access unavailable)
8
Q
Side effects
A
- Nausea
- Vomiting
- Skin rash
9
Q
Special notes
A
Usual dose
- adult 1 g
- child 50 mg/kg (max 1 g)
IV dose must be made up to 10 ml using sterile water and dose administered over 2 mins
IM dose must be made up to 4 ml using 1% lignocaine and dose administered in lateral upper thigh
10
Q
IM/IV effects
A
Onset: n/a
Peak: n/a
Duration: n/a
