Dexamethasone Flashcards

1
Q

Presentation

A

8 mg in 2 ml glass vial

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2
Q

Pharmacology

A

Cortiocosteroid secreted by the adrenal cortex

Actions:

  • Relieves inflammatory reactions
  • Provides immunosuppression
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3
Q

Metabolism

A
  • by the liver and other tissues

- excreted predominantly by the kidneys

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4
Q

Indications

A
  • Bronchospasm associated with acute respiratory distress not responsive to nebulised salbutamol
  • Moderate - severe croup
  • Acute exacerbation of COPD
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5
Q

Contras

A

Known hypersensitivity

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6
Q

Precautions

A

Solutions which are not clear or are contaminated should be discarded

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7
Q

Route of administration

A

IV (administered over 1-3 minutes)

Oral

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8
Q

Side effects

A

Nil of significance in the above indication

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9
Q

Special notes

A

Does not contain an antimicrobial agent, therefore use solution immediately and discard any residue

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10
Q

IV effects

A

Onset: 30-60 mins
Peak: 2 hours
Duration: 36-72 hours

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11
Q

Severe asthma

A

8 mg IV/Oral single dose only

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12
Q

COPD

A

8 mg IV/Oral single dose only

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13
Q

Croup

A

600 mcg/kg Oral (max 12 mg) - single dose only

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