Glomerular FIltration Flashcards

1
Q

the 2 basic renal processes:

A

filtration

reabsorption

secretion

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2
Q

how much blood to the kidneys receive (on average) per day?

What percentage is this of cardiac output?

A

1200mls/min

20-25%

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3
Q

none of the red cells and only a fraction of the plasma is filtered through the ……… ……….

the remainder passes via the ……… ………. into the …….. …………. then into the renal vein

A

bowmans capsule

efferent arterioles

peritubular capillaries

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4
Q

plasma constitutes ……..% of total BV

A

55

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5
Q

if plasma is 55% of BV and total BV to the kidney is 1200mls/min - what is the renal plasma flow?

A

660mls/min

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6
Q

GFR is usually what?

A

125ml/min

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7
Q

what is glomerular filtration dependent on?

A

starlings forces

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8
Q

what are the starling forces that must remain balances in glomerular filtration?

A

hydrostatic forces

oncotic forces

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9
Q

oncotic forces favour……..

A

reabsorption

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10
Q

hydrostatic forces favour……

A

filtration

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11
Q

why is the glomerular capillary pressure higher than in most other capillaries in the body?

A

the afferent arteriole is short and wide and offers little resistance to flow

(efferent arteriole is opposite - long and narrow)

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12
Q

‘golden rule of circulation’

if you have a high resistance - hydrostatic pressure upstream is ……….. while the pressure downstream is ………..

A

increased

decreased

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13
Q

at the glomerular capillaries - the hydrostatic pressure always exceeds the ……….. ……….

A

oncotic pressure

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14
Q

what is it that occurs at the glomerular capillaries?

and nothing else!

A

glomerular filtration

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15
Q

arterioles are subject to extrinsic control via

A

sympathetic VC nerves

circulating catecholamines

angiotensin II

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16
Q

relative diameter of efferent and afferent arterioles (and therefore the balance between them) are crucial in determining…….

A

GFR

17
Q

What two factors are essential in auto-regulation?

A

BP

GFR

18
Q

the peritubular capillaries are responsible for ………

A

reabsorption

19
Q

what is filtration at the glomerular capillaries?

A

formation of a protein-free filtrate of plasma

20
Q

what is secretion at the glomerular capillaries?

A

removing things the body doesn’t want

secreted into the proximal and distal tubule