Global health Flashcards

1
Q

What is the under 5 mortality rate?

A

probability of a child born in a specific year or period dying before the age of 5

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2
Q

What is the infant mortality rate?

A

probability of a child born in a specific year or period dying before the age of 1
expressed as rates per 1000 live births

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3
Q

List 5 global causes of under 5 mortality?

A
diarrhoea
pneumonia
pre term birth complications
neonatal sepsis
intrapartum related complications
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4
Q

What are the antinatal measures put in place to protect newborns?

A

tetnus vaccine

treatment of maternal infections including HIV and syphilus

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5
Q

What are the preterm labour measures put in place to protect newborns?

A

steroids

antibiotics for sepsis and pneumonia

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6
Q

What are the common pathogens that cause Pneumonia in newborns?

A

strep penumoniae
haemophilius influenzar
RSV
pneumocystis jirvoeci

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7
Q

What pathogen in immunised against for pneumonia?

A

pneumocystis jirvoeci

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8
Q

What are the risk factors of pneumonia?

A

malnutrition - weakens the immune system
overcrowding - droplet spread
indoor air pollution - indoor fires
parental smoking - increases risk x 2.5

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9
Q

What type of infants are most likely to get pneumocystis jiroveci pneumonia?

A

HIV infected

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10
Q

What pathogens most commonly cause Diarrhoea?

A

rota virus

E.coli

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11
Q

How is diarrhoea treated?

A

oral rehydration solution

zinc supplements

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12
Q

What are the signs of HIV?

A
recurrent or severe common childhood illness - eg diarrhoea 
recurrent oral candidiasis 
recurrent severe bacterial infections
failure to thrive
persistant fever
encepalopathy 
chronic parotitis
generalised lymphadenopathy
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13
Q

How is HIV diagnosed when <18mnths?

A

virological PCR for HIV DNA or RNA

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14
Q

How is HIV diagnosed when >18mnths?

A

serological rapid antibody test - this is unreliable for under 18mnths due to mothers antigens being passed on due to breastfeeding

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15
Q

What is done after the initial diagnostic tests?

A

stage from 1-4

do CD4 count

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16
Q

How is HIV treated?

A

2NRTIs = nucleotide reverse transcriptase inhibitor (abaclavir and iamivudine)
2NNRITs - non nucleotide reverse transcriptase inhibitor (efavirenz for >3yrs, kaletra <3yrs)

17
Q

What are the side effects of HIV treatment?

A

immune reconsitution inflammatory syndrome

18
Q

What is the common presentaion of malaria?

A

pallor

fever

19
Q

How is malaria diagnosed?

A

blood film for microscopy

20
Q

What is the most severe form of malaria?

A

P.falciparum