Glands Introduction Flashcards

1
Q

Define a gland

A

An epithelial cell or aggreate of a cell that are specialised for the secretions of a substance

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2
Q

W what are three features of an endocrine gland ?

A

1) secrete directly into the blood
2) secrete hormones

3 all epithelial cells secrete hormones from the gland

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3
Q

What is the main endocrine gland called ?

A

Pituitary gland

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4
Q

Where is the pituitary gland located ?

A

Beneath the hypothalamus

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5
Q

What are two examples of hormones that the posterior pituitary gland secretes ?

A

1) oxytocin

2) ADH ( vasopressin)

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6
Q

What are 5 examples of hormones that are secreted by the anterior pituitary gland ?

A

1) T-SHIRT ( thyroid stimulating hormone )
2) adrenocorticotropin hormone
3) LH
4) follicle stimulating hormone
5) prolactin

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7
Q

Give 5 examples of exocrine glands

A

1) mammalian gland
2) salivary gland
3) sweat gland
4) sebaceous gland
5) lachymal gland

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8
Q

What is myoepithalial cells ?

A
  • found in glands that are often a mixture of exocrine and endocrine
  • they have features of smooth muscle and epithelial cells.
  • they help eject secretions from the duct
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9
Q

What type of duct does not exist in an adult ?

A
  • simple alveolar
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10
Q

What are the three modes of secretion ?

A
  • merocrine
  • apocrine
  • Holocrine
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11
Q

What is merocrine secretion and give an example ?

A

1) vesicles fuse with the plasmolemma and released through the process of exocytosis.

  • an example would be insulin secretion
  • this is where ATP increase blocks sensitive k+ channels which causes depolarisation in the beta cell which causes Ca2+ channels open causing ca2+ to enter.
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12
Q

What is apocrine secretion ?

A
  • partial loss of cytoplasm
  • only fats are secretes by apocrine glands
  • for example mammary glands during lactation period , sweat glands in underarms and genitalia.
  • lipid comes. Into contact with apical membrane and pushes against it.
  • thin layer of apical membrane surrounds it.
  • this membrane then pinches off the cell.
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13
Q

What is holocrine secretion and give an example ?

A

Complete loss of cytoplasm.

  • an example would be the sebaceous gland in the skin and tarsal gland in the eyelid.
  • secretarory cells fill up with secretory granules.
  • the cell organelles degenerate and cell dies.
  • plasma membrane breaks and cell empties contents
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14
Q

Wheat are the three destinations the contents of Golgi apparatus ?

A

1) vesicles
2) some retained for use inside cells
3) some enters plasma membrane

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15
Q

Pdefine glycosylation

A

Use of enzymes to covalently attach sugars to lipids and proteins.

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16
Q

What are 4 roles of glycolysation ?

A

1) prevent protein digestion by protease
2) prevent lipid digestion by lipases
3) aid protein folding
4) aid cell recognition

17
Q

Define exocytosis

A

Secretion of molecules outside the cell through vesicles fusing to a membrane

18
Q

Define endocytosis

A

Engulfing of molecules inside the cell via vesicle formation

19
Q

Define phagocytosis

A

The process by which phagocytes engulf / envelop other cells

20
Q

Define pinocytosis

A
  • process in which liquid droplets are indigested by cells.
21
Q

What form of transepithalilal transport do impermeable substances use ? Eg cholesterol

A
  • this is where material is endocytosed at one end of the surface and exocytosed at another end.
22
Q

What what form of transepithalial transport do amino acids use ?

A
  • they move through the intracellular junction
23
Q

What form of transepithelilal transport do steroid hormones use ? Eg testosterone , oestrogen , progesterone

A

Directly through the lipid membrane

24
Q

How is thyroxine transported across the epithelium?

A
  • via carrier proteins