Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

step > GIpharm > Flashcards

GIpharm Flashcards

1
Q

Cimetidine/Ranitidine

A

H2 blocker

BLock histamine H2 receptors -> dec acid release by parietal cells

Toicity: Cimetidine inhibits P450, inc impotence, gynecomastia

Crosses blood brain barrier and placenta. Dec GFR

Other H2 blockers no side effects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Omeprazole/lansoprazole

A

Proton pump inhibitor

Stop H+/K+ ATPase in parietal cells

Increased risk of C. difficile infection, pneumonia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Bismuth

A

Binds ulcer to provide protection and allows HCO3 to reestablish pH gradient

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Sucralfate

A

Binds ucler base, providing protection and allowing HCO3 to reestablish pH gradient

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Misoprostol

A

PGE1 analog -> Increased mucous barrier and dec acid production

Toxcity: Diarrhea, contraindicated in pregnancy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Octreotide

A

Somatostatin analog

Toxicity: Nausea, cramps, steatorrhea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Aluminum hydroxide

A

Antacid

Toxicity: Hypokalemia, constipation, seizures, osteodystrophy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Magnesium hydroxide

A

Antacid

Toxicity: Hypokalemia
Diarrhea, hyporeflexia, hypotension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Calcium carbonate

A

Antacid

TOxicity: Hypercalcemia, hypokalemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Magnesium hydroxide

A

Inc osmotic load to draw out water

Toxicity: Diarrhea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Magnsium citrate

A

Inc osmotic load to draw out water

Toxicity: Diarrhea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Polyethyle glycol

A

Inc osmotic load to draw out water

Toxicity: Diarrhea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Lactulose

A

Inc osmotic load to draw out water

also vs hepatic encephalopathy

Toxicity: Diarrhea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Infliximab

A

Monoclonal antibody vs TNF alpha

Use: Crohn’s disease, ulcerative colitis

Toxicity: Infection -> Latent TB reactivation, fever

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Sulfasalazine

A

Antibacterial and anti inflammatory

Used vs UC/Crohns disease

TOxicity: Malaise, nausea, oligospermia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Ondansetron

A

5HT antagonist, antiemetic

Use: Stop vomiting

Toxicity: headache, constipation

17
Q

Metoclopramide

A

D2 receptor antagonist -> Inc resting tone, contractility, motility. Does not inflluence colon transport time

Use: Gastroparesis, antiemetic

Toxicity: Parkinson effects, restlessness, drowsiness, fatigue, depression

Interacts with digoxin and diabetic agents

COntraindicated in small bowel obstruction or parkinsons disease

step (19 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions