giardiasis, histolytic, visceral leishmanias Flashcards
clinical symptoms L.donovani
fever
splenomegaly
pancytopenia
morphological forms of l.donnovani
amastigote (human) promastigote (sandfly)
species of leishmania
l. donnavani donnovani - inida
L. Infantum - europe
L. chagasi -south america
cells affected in l.donnovani
RES+ macrophages
treatment for L. donovani
gucantime, amphotreicin B,pentamidine, miltefosine , allopurinol
is visceral leishmaniasis a zoonosis or anthroponosis
zooinos
name of disease caused by e.histolytica
amoebiasis
different forms of e.histolytica in humans
intesinal : diarrhea,
extraintestinal: liver abscess,fever
trophozoite form of e. histolytica
forma magna - invasive form invades the mucosa
forma minuta- aymptomatic, commensal
infective form of e.histolytica
cyst (quadrinucleate)
target of e. histolhyitca
large colonn
treatment for e.histolytica
metronidazole/tinidazole- relief of symptoms, kill trophozoites but not cysts
iodoquinol/paromycin- kill cysts
important severe complication of histolyitca
toxic megacolon
IP e.histolyitca
intestinal l- 1-4 weeks
extraintestinal - variable
IP e.histolytica
intestinal l- 1-4 weeks
extraintestinal - variable
where does lambia live
duodenum and upper jejanum
infective form of lamblia
cyst
IP of lamblia
2 weeks
which parasite has a falling leaf pattern on microscopy
G.lamblia
treatment for giardiasis
metronidazole\tinidazole
naegleriasis causative agent
naegleria fowleri
mode of entry of naegleria
nose- CNS (olfactory nerve)
fatal consequence of naegleria
PAM primary amoebic meningoencephalitis
morphological forms of naegleria
- cyst 2. trophozoite 3. flagellated form
what kind of water does naegleria
freshwater lakes streams
treatment for naegleriasis
not optimal, just use a combo
antifungals, miltefosine, amphotericin B
acanthamebiasis leads to
GAE
Treatment for acanthamoebiasis
corneal debridement
keratoplasty
topical chlorhexidine
Mao humans get visceral leishmanias
bite of sandfly and sanfly regurgitates promastigoTes into the wound this is because they have difficulty sucking blood as they are blocked by the enormous numbers of promastigoTes
causes of anemia in kala azhaar
splice sequestration
Bm infiltration
autommune hemolysis
hemorrgae
morphology of leishamani
flagellete protozoa
which type of leishmania is not a zooinot
l. donnovani the Indian type