filarial nematodes

Question 1

IF river blindness

Answer 1

microfilaria

Question 2

treatment of river blindness

Answer 2

Check for confection with loa loa
to kill microfilaria - ivermectin
to kill the macrofilaria - doxycycline

Question 3

vector of river blindness

Answer 3

black fly female

Question 4

eye problems in river blindness

Answer 4

begins commonly as photophobia to blurring of vision 
anterior  uveitis
 slerosing keratitis 
chorioretinitis 
optic nerve neuritis 
 snowflake keratitis

Question 5

where do adults live in river blindness

Answer 5

s.c nodules

Question 6

geography of river blindness

Answer 6

sub suharran africa - west and central but small foci in Yemen +venzuela

Question 7

name of the parasite in river blindness

Answer 7

onchocerca volvulus

Question 8

skin findings in river blindness

Answer 8

onchocercoma - asymptomatic nodules where adults are

dermatitis due to the MF = ITCHING, EXCORIATIONS, CRUSTING, LICHENIGICATION
lizard skin, leopard skin
‘hanging groin’

Question 9

diagnosis of river blindness

Answer 9

slit limp examination - MF
skin biopsy - mf in skin
palpable nodules - excise adults
SEROLOGY LIMITED VALUE

Question 10

main cause of symptoms in river blindness

Answer 10

MF

Question 11

main cause of symptoms in loa loa

Answer 11

adults

Question 12

vector of loa loa

Answer 12

tabard lie (day biting)

Question 13

skin findings in loa loa

Answer 13

malabar swellings anywhere in body but usually extremities +joints

sometimes can see the moving worms

Question 14

symptoms of loa loa

Answer 14

Subconjunctival worms<15 along with painless edema, proptosis , ocular granuloma
angioedema - malabar swellings
nephropathy - proteinuria main symptom
encephalopathy- mild

Question 15

diagnosi of loa loa

Answer 15

day time (10am-2pm)- microfilaria
worm in eye
serology

Question 16

treatment of loa

Answer 16

1. need to check co infection with river blindness

Need to check the level of microfilaria in the blood if it’s less than 8000 you can treat with a DEC if it’s more than 8000 you need to 1st reduce the number with albendazole then afterwards can use DEC

Question 17

example of diurnal peridocity

Answer 17

loa loa

Question 18

example of non periodic

Answer 18

onchocerciasis

Question 19

where are mF found in river blindness

Answer 19

typically in skin and sc lymphatics around the vciitnty of adult worms

Question 20

mazotti reaction

Answer 20

associated with river blindness and treatment with DEC , fever, urticaria, lyphadenomegaly