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CPT Drugs > GI Pharmacology > Flashcards

GI Pharmacology Flashcards

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NASM ® CPT flashcards
1
Q

PPI

A

Omeprazole, Lansoprazole

Peptic Ulcer disease

Irreversibly inhibits H/K ATPase in parietal cells

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2
Q

PPI issues?

A

Abdo pain, Constipation/diarrhoea

Masks symptoms of gastro-oesophageal cancer

Omeprazole is a CYP inhibitor -
reduces clopidogrel activation
Increased effects of warfarin / phenytoin

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3
Q

H2 Receptor antagonists

A

Ranitidine

Inhibits H2 at parietal cells - reduced histamine

CURRENT LARGE SCALE RECALL ON RANITIDINE PRODUCTS

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4
Q

Gaviscon

A

Alginic acid + antacid

Buffers stomach acid

Magnesium Carbonate - Diarrhoea
Aluminium hydroxide - Constipation

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5
Q

Aminosalicylates

A

Mesalazine

Ulcerative colitis - 1st line treatment

Releases 5-aminosalicylic acid (anti-inflammatory)

Enteric coated - topical action at colon

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6
Q

H Pylori treatment

A

Lansoprazole + clarithromycin + Amoxicillin/metronidazole

(+ve urea breathe test)

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CPT Drugs (19 decks)

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