GI (liver) Flashcards
describe patho related to portal HTN
portal HTN results in venous congestion and dilation. pressure builds up in systemic venous circulation, causes congestion where portal and systemic venous system connect (esophagus, stomach, rectum)
important functions of the liver
synthesize albumin (maintains oncotic pressure)
eliminates bilirubin
coagualtion factors!! (impaired clotting is dysfxn)
what lab is most reflective of liver failure
high serum ammonia
inflammatation of the liver caused by virus, bacteria, drugs, alcohol, toxins
hepatits
treatment for hepatitis
supportive : rest, nutrition, avoid stress and hepatotoxic substances, treat cause
liver condition with chronic inflammation, circulationa dn structure changes, and alterations in metabolic processes
cirrhosis
what is cirrhosis caused by
chrinic active hepatitis, biliary obstruction, and unknown!
what is cirrhosis most commonly caused by?
chronic alcohol abuse
what does portal HTN result in poor metabolism of?
nutrients
drugs
toxins
where do vascular changes occur with portal HTN?
esophagus, stomach, rectum
assessment findings for impaired liver fxn
jaundice
edema
fatigue
bruising
ascites
importatn lab findings in impaired liver fxns
inc. ALT/AST
inc. ammonia
what is a reversible dec. in neuro fxn related to liver probs
hepatic encephalopathy
what causes hepatic encephalopathy
accumulation of ammonia and neurotoxins
what is an early sign of hepatic encephalopathy
asterixis (hand flapping, can not keep them up)
what meds are given for hepatic encephalopathy
lactulose, neomycin, rifaximin
accumulation of fluid in the peritoneum
ascites