fluid & electrolytes (worksheet/basics) Flashcards
weight in oliguric phase of acute tubular necrosis
up
total fluid balance in oliguric phase of acute tubular necrosis
up
urine output in oliguric phase of acute tubular necrosis
down
urine osmolality in oliguric phase of acute tubular necrosis
up
serum BUN/creatinine in oliguric phase of acute tubular necrosis
up
serum osmolality in oliguric phase of acute tubular necrosis
down
how are urine output and osmolality related
inverse (if one is up, the other is down)
what should you think of serum osmolality as?
amount of salt
potential electrolyte imbalances in oliguric phase of acute tubular necrosis
hyperkalemia, hyponatremia, hypocalcemia, hyperphosphatemia
potential complications in oliguric phase of acute tubular necrosis
fluid overload!
cardiac arrythmia
CVP/wedge increased
treatment in oliguric phase of acute tubular necrosis
stop cause
maintain fluid balance
CRRT
weight in diuretic phase of acute tubular necrosis
down
total fluid balance in diuretic phase of acute tubular necrosis
down
urine output in diuretic phase of acute tubular necrosis
up
urine osmolality in diuretic phase of acute tubular necrosis
down
serum BUN/creatinine in diuretic phase of acute tubular necrosis
trend down / start normalizing
serum osmolality in diuretic phase of acute tubular necrosis
up
potential electrolyte imbalances in diuretic phase of acute tubular necrosis
hypernatremia!
hypokalemia
potential complications in diuretic phase of acute tubular necrosis
dehydration!
dysrhythmias
treatment in diuretic phase of acute tubular necrosis
hydration to replace loss
electrolytes
which F&E problems have the same characteristics?
(in terms of weight, urine output, etc.)
SIADH looms the same as oliguric phase of acute tubular necrosis
DI looks the same as diuretic phase of acute tubular necrosis
what to question when looking at phases of third spacing?
where is the fluid?
where is the fluid in phase 1 (loss) of third spacing
none in vascular spade, all in interstitial
weight in phase 1 (loss) of third spacing
up (in wrong place)
total fluid balance in phase 1 (loss) of third spacing
up
urine output in phase 1 (loss) of third spacing
down
urine osmolality in phase 1 (loss) of third spacing
up
serum BUN in phase 1 (loss) of third spacing
up
serum osmolality in phase 1 (loss) of third spacing
up
potential electrolyte imbalances in phase 1 (loss) of third spacing
hypernatremia
hyperkalemia
potential complications in phase 1 (loss) of third spacing
renal hypoperfusion, no fluid
treatment in phase 1 (loss) of third spacing
IV fluids
albumin! same as colloids
how does albumin help in phase 1 (loss) of third spacing
pulls from interstitial to vascular
weight in phase 2 (reabsorption) of third spacing
down (start urinating)
total fluid balance in phase 2 (reabsorption) of third spacing
down
urine output in phase 2 (reabsorption) of third spacing
up
urine osmolality in phase 2 (reabsorption) of third spacing
down
serum BUN in phase 2 (reabsorption) of third spacing
back to normal
serum osmolality in phase 2 (reabsorption) of third spacing
low or normal
potential electrolyte imbalances in phase 2 (reabsorption) of third spacing
hypokalemia
sodium returning to normal or slightly low
potential complications in phase 2 (reabsorption) of third spacing
vascular fluid overload!
pulmonary status concern
treatment in phase 2 (reabsorption) of third spacing
assess for overload (dec. fluids/diuretics if so)
look at net balance to determine intake
weight in SIADH
up
total fluid balance in SIADH
up
urine output in SIADH
down
urine osmolality in SIADH
up
serum osmolality in SIADH
down (only holding water, dilutes sodium)
ADH relationship to salt and water
ADH only deals with water NOT SALT
SIADH = ?
soaked inside
too much ADH
potential electrolyte inbalances in SIADH
hyponatremia!!
potential complications in SIADH
Sodium = Seizures!!!
Stop urinating
coma/death
treatment in SIADH
fluid restriction
sodium replacement (hypertonic saline!)
demeclocycline (side effect interferes with ADH)
Stop fluids, give Salt
what med has a side effect that interferes with ADH to help SIADH
demeclocycline
DI = ?
dry inside
nothign to do with blood sugar!
weight in diabetes insipidus (DI)
down
total fluid balance in diabetes insipidus (DI)
down (peeing lots)
urine output in diabetes insipidus (DI)
up
urine osmolality in diabetes insipidus (DI)
down
serum osmolality in diabetes insipidus (DI)
up
potential electrolyte imbalances in diabetes insipidus (DI)
hypernatremia
potential complications in diabetes insipidus (DI)
seizures, coma, death (sodium)
treatment in diabetes insipidus (DI)
hypotonic fluids
vasopressin (same as ADH)
hydrochlorothiazide (only is caused by kidneys)
what is a “quick fix” to maintain stability
CRRT
heparin use in CRRT and probs
can be used in the circuit to prevent clots, can cause HIT -> watch platelets
functions of the kidneys
1) eleimination of metabolic waste
2) BP regulation
3) erythrocyte production
4) vitamin D activation
5) acid/base balance
what is GFR dependen on?
blood flow
normal GFR?
125
GFR levels of dec. kidney fxn and kidney failure
< 100 = dec. fxn
< 15 = failure
which fluid compartment is accessed IV
extracellular fluid
describe isotonic, hypertonic, and hypotonic fluids in relation to plasma
isotonic = same concentration as plasma
hypertonic = > plasma concentration
hypotonic = < plasma concentration
isotonic crystalloids
0.9% NaCl
LR
hypertonic crystalloids
3% NaCl (monitor close)
D5 NaCl (D5 normal)
D5 in LR (D5LR)
D5 0.45% NaCl (D5 half normal)
hypotonic crystalloids
0.25% NaCl
0.45% NaCl
examples of colloids
25% albumin
hetastarch
blood prodicts
what do colloids do to fluid
pull fluid into intravascualr space
Condition defined by:
decline in GFR
retention of products normally excreted
electrolyte imbalance
acid/base abnormality
fluid volume disruption
AKI
normal BUN
10-20
which AKI is any renal hypoperfusion from dec. cardiac output, hemorrhage, vasodilation, thrombosis, etc.
pre-renal AKI
which AKI is any condition that produces ischemic or toxic insult directly at site of nephron
intra-renal AKI
which AKI is any obstruction that hinders flow of urine after the kidney
post-renal AKI
potential causes of post-renal AKI
kidney stones, catheter blockage, tumor
which kind of acute tubular necrosis (ATN) results from prolonged hypoperfusion?
ischemic ATN
which ATN results when concentration of nephrotoxin causes necrosis of tubular cells
nephrotoxic ATN
potential causes of nephrotoxic ATN
vancomycin
aminoglycosides
zosyn
contrast dye
what is important to prevent nephrooxic ATN?
monior peaks and troughs of risk meds
which phase of ATN is period from initial insult until cell injury occurs, ischemia injury is evolving
onset phase
which ATN phase results from necrotic cellular debris blocking formation of urine and removal of wastes
oliguric/anuric phase
which phase of ATN is characterized by increase in GFR
diuretic phase
main goal of AKI treatment
restore and maintain electrolye imbalance
contraindications for hemodialysis
hemodynamic instability
inability to coagulate
lack of access
what is used if dialysis is contraindicated?
CRRT
why is CRRT better if hemodialysis is contraindicated?
filters smaller amount of blood over longer times
what is the end result of the loss phase of third spacing?
fluid moves into interstitial space
which DI is when posterior pituitary fails to release ADH?
central DI
which DI is inability of kidney to respond to ADH
nephrogenic