GI investigations Flashcards
What are the principles of GI investigation?
Thorough history and exam
Differentiate functional and structural disorders
Start with simple and noninvasive if possible
Justify all investigations requested
What bedside investigations can be done?
BMI Pulse ox ECG Capillary glucose Urinalysis
What are the types of stool analysis?
FOB
Stool culture
Faecal calprotectin
Faecal elastase
When is faecal calprotectin used for?
Raised in inflammatory conditions
Useful for monitoring disease activity
What is faecal elastase used for?
Pancreatic insufficiency
Malabsorption
What blood investigations can be done for GI conditions?
U+E Ca and Mg LFT CRP Thyroid function FBC Coagulation Haematinics Hepatic screen Coeliac serology Tumour markers
What do we check Ca and Mg for?
Malabsorption
What does CRP help us differentiate between?
Rise in Crohn’s
No rise in ulcerative colitis
What does FBC help us check for?
Anaemia
White cell count- rise in IBD
Platelet count- IBD, neoplasia
What do haematinics check for?
B12
Folate
Ferritin
What do we check in a hepatic screen?
Hep B and Cserology Autoantibodies Immunoglobulins Ferritin Alpha 1 antitypsin copper
What tumour marker is checked for and what is the main use?
CEA
Monitoring response to therapy in some colorectal cancers
What physiology investigations can be done?
Urea breath test- H pylori
Hydrogen breath test- bacterial overgrowth
Lactose intolerance
Oesophageal pH and manometry
What endoscopic investigations can be done?
Upper GI endoscopy Colonoscopy ECRP Endoscopic ultrasound Enteroscopy
What does a UGIE examine?
Oesophagus to duodenum