GI: GI, Dental, Eye Flashcards
Diverticulitis / Diverticular disease
related digestive conditions that affect the large intestine
small bulges or pockets that can develop in the lining of intestine as people age - usually asymptomatic, called diverticulosis
What are the causing symptoms of diverticulitis?
Pain in abdomen and becomes diverticular disease
What does treatment of diverticulitis cover?
dietary manipulation, symptomatic medication and progress further to e.g. surgery
Acute diverticulitis
if becomes inflammed and infcted symptoms incl;
constant, more severe abdominal pain
pyrexia
diarrhoea or constipation
mucus or blood in stools or somethimes rectal bleeding
When to refer?
arrange same-day hospital assessment in IF PERSON;
uncontrollable abdominal pain
dehydrated to take or tolerate oral fluids at home
unable or at risk of dehydration is unable to take tolerate oral fluids at home
unable to take or tolerate oral antibiotics if needed at home
aged over 65 yrs
significant comorbidity or immunosuppression
When to offer antibiotic if person with acute divertucullitis?
systemically unwell - and does not meet the criteria for suspected complicated acute diverticulitis
What to prescribe if treating with oral antibiotic?
prescribe co-amoxiclav 500/126 mg tds for 5 days
pen allergic;
cefalexin 500mg bd pr tds for 5 days (up to 1-1.5g a day, or qds) + metronidazole or trimethoprim + metronidazole 400mg tds daily for 5 days
Gastroenteritis
transiet disorder due to enteric infection with viruses, bacteria or parasites
sudden onset diarrhoea, faecal urgency, bloods/mucus in stools
nausea/sudden onset vomiting
fever or general malaise
abdominal pain/cramping
can be addovciated with; headache, myalgia, bloating, weight loss
Gastroenteritis – key questions to ask
Symptoms (as above)
Onset, frequency, severity
Risk factors for dehydration – reduced fluid intake, reduced urine output
Recent food intake
Recent exposure to contaminated water
Recent foreign travel
Contact with other suspected cases
Recent antibiotic/PPI use
Occupation
Gastroenteritis causes
Transmission of gastrointestinal infection from person-to-person may occur through one or more of a variety of different pathways, including faecal-oral, foodborne, environmental, and airborne routes
Most often self-limiting in a day or so and caused by a virus
However, can be bacterial or parasitic
Bacterial causes - Gastroenteritis
- Campylobacter
- E.coli
- Salmonella
- shigella (resolves in 5-7 days)
- c. difficile (10 day course of antibiotics)
Parasites
Cryptosporidiosis = transmitted by animal-to-human or human-to-human contact, by occupational or recreational exposure to contaminated land or water, or by consuming contaminated water or food
lasts for 1-2 weeks
Giardiasis = can be transmitted by person-to-person spread by the faecal-oral route; by contact with the faeces of infected animals; by consumption of contaminated food or drink; waterborne including swimming in contaminated water; or by sexual transmission, particularly among men who have sex with men
Stop the DAMN drugs (where appropriate):
if vomiting or diarrhoea for more that a day
Diruretics
ACEi/ARB
Metformin (and other antidiabetics e.g. SGLT2i, gliclazide)
NSAIDs
Treatments - Gastroenteritis
Oral re-hydration therapy, e.g. Dioralyte
first-line therapy even when referring
under 1 yr - 50ml
1-5 yrs - 100ml
6-12 yrs - 200ml
adult - 400ml
Antimotility drugs not routinely recommended and contraindicated if:
blood/pus/mucous present in stools
high fever
confirmed infection with Shigella or certain E.coli strains
Antibiotics not routinely recommended but may be recommended in certain severe cases of confirmed bacterial infection
Campylobacter: clarithromycin 250–500 mg twice daily for 5–7 days, within 3 days of onset of illness
E. coli: no effective antibiotic treatment available for Shiga toxin-producing E. coli (STEC) infection
Salmonella: antibiotic treatment is not usually needed
Shigella: specialist advice needed
C. difficile: depends on infection, but vancomycin most common
Cryptosporidiosis: no specific treatment licensed in the UK
Giardiasis: tinidazole 2g as a single dose