CVS - cardiac rhythms Flashcards
each side of the transport system?
- pulmonary
- systemic
What factors affect cardiac output?
- pregnancy
- excerise
- respiration
- age
What is responsible fort the blood supply?
4 coronary arteries supply blood to the heart muscle
- right/ left coronary artery
What are the types of myocardial infraction? (MI)
1) spontaneous infraction related to ischaemia due to a primary coronary event such as plaque erosion and rupture
2) Mi secondary to ischaemia due to either ^ oxyfen demand or dec. supply
3) sudden unexcpected cardiac death
4) MI associated with percutanous coronary intervention
5) Mi associated w cardiac surgery
6) multifactorila aetiology, acute or chronic based on change in cardiac troponin concentrations w serial testing
STEMI
ST elevation
What happens in cardiac pacemaker cells?
- intrinsic cardiac conduction system
- Gap junctions
- intracellulcar calcium channels
- voltage dependant calcium chanel in the plasma membrane
depolarisation means…
a wave of positive charge
What change effects AP
chnage in Na, Ca, K
Absolute refractory period (ARP)
the cell is completely unexcitable to a new stimulus.
Effective refractory period (ERP):
ARP + short segment of phase 3 during which a stimulus may cause the cell to depolarize minimally but will not result in a propagated action potential (i.e. neighbouring cells will not depolarize).
Relative refractory period (RRP):
greater than normal stimulus will depolarize the cellandcause an action potential.
Supranormal period
ahyperexcitableperiod during which a weaker than normal stimulus will depolarize the cells and cause an action potential
Sinus Node
Primary pacemaker
Fires at a rate of 60-100 depolarisations per minute
AV node
Base of RA
Fires at a rate of 40-60 dpm
Ventricular (Bundle of His)
Right and left branches
Fires at a rate of 20-40 dpm
Ventricular (Purkinje Fibers)
Less than 40 dpm
main components of an ECG? (letters)
P, Q, R, S, T
PR segment
Pause between SA and AV node
ST segment
Should be at isoelectric line if elevated more than 2 small boxes (2mV) could signal issues infarction or ischaemia
PR Interval
Normal 0.12-0.20s [3-5 little boxes]
SAN firing - depolarisation of atria - pause at AV node
QRS Interval
Normal <0.10 [2.5 little boxes])
Depolarisation of the ventricles and repolarisation of the atria (pump efficiency
QT Interval
normal >440ms ♂ or >460ms ♀ @60bpm
N.B. RATE DEPENDENT need to calculate corrected QT (Bazett formula)
If QT prolonged then youre trying to contract a heart that is still trying to _____
atrial ectopic focus
relax
___________ occurs at a pacemaker cell (not SAN) close to or further away from AV node than the SAN
depolaristaion
What factors sffect QT interval
- Plasma Ca
- Medicatioms - amplodipine (affects ion channels)
- Genetics - mutations in LQT1/2/3
hypercalcemia
short QT interval
Hypocalemia
long QT interval
Dysrhythmia
Impulse formation
Altered conduction
What does an Abnormal ECGs look like?
- characteristic shape-change in an ECG
- other conditions results in changes in cardiac rhythm