GI Exam 2 (Signs)

Question 1

Gilbert Syndrome

Answer 1

Jaundice

Mild condition in which the liver does NOT properly process bilirubin

Question 2

Critter-Najjar Syndrome

Answer 2

Jaundice

A rare inherited disorder affecting the metabolism of bilirubin

Question 3

Acetaminophen Toxicity (Most common)

Encephalopathy AND Imparied Synthetic Function (INR > 1.5)

Answer 3

Acute Liver Failure

Question 4

Presence of ___________ is diagnostic of acute illness (HAV)

Answer 4

IgM anti-HAV

Question 5

Hallmark of infection (HBV)

Answer 5

HBsAg = Surface antigen

Question 6

HBV

Anti-HBs = antibody to HBsAg

Answer 6

Post-clearance and after successful vaccination

Question 7

IgM anti-HBc =

IgG anti-HBc =

Answer 7

Acute HBV

Chronic HBV

Question 8

HBeAg + 3 months =

Answer 8

Chronic HBV

Question 9

Confirmatory Lab for HCV

Answer 9

Anti-HCV EIA (POS) —> PCR (Confirmatory)

Question 10

Hepatitis

Severe in pregnant patients

Answer 10

E

Question 11

ONLY in association w/ HBV Infection

Answer 11

HDV

Question 12

Caput Medusae

C-B Murmur

Answer 12

Cirrhosis

Question 13

Chronic Anovulation
Amenorrhea

Impotence, Infertility
Gynecomastia

Answer 13

Cirrhosis (Endocrine)

Question 14

CBC — Thrombocytopenia

Hepatic Panel — Hypoalbuminemia

Answer 14

Cirrhosis

Question 15

Accumulation of iron

Answer 15

Hemochromatosis

Question 16

Kaiser-Fleischer Rings — Brownish or greenish ring at the corner-scleral junction

Answer 16

Wilson Disease

Question 17

Acute Cholangitis

Charcot Triad —>

Reynolds Pentad —>

Answer 17

Charcot Triad —> Acute Cholangitis

RUQ pain, Fever/Chills, Jaundice

Reynolds Pentad —> Acute SUPPURATIVE Cholangitis (Surgical Emergency)

Charcot Triad + Altered Mental Status + HOTN

Question 18

Courvoisier sign, painless, often w/ dilated biliary tree

Palpable gallbladder w/ painless obstructive jaundice

“Normal” alpha-fetoprotein

Answer 18

Carcinoma of the Biliary Tract (Cholangiocarcinoma)

Question 19

Cullen’s Sign or Grey-Turner Sign

Answer 19

Acute Pancreatitis (Severe)

Question 20

Abd pain, Jaundice, Weight loss + Courvoisier sign

Answer 20

Pancreatic Cancer

Question 21

Lab: CA 19-9

Answer 21

Pancreatic Cancer

Question 22

Autoimmune Hepatitis

Extrahepatic Manifestations

Answer 22

Arthritis
Sjogren syndrome
Thyroiditis
Nephritis
Ulcerative Colitis
Coombs-positive hemolytic anemia

INC risk of cirrhosis & cancer