GI Disorders Flashcards
physiologic reflux
- Occurs after eating
- Is short lived
- Rarely occurs during sleep
pathologic reflux
- Associated with symptoms
- Associated with mucosal injury
- Nocturnal symptoms
3 mechanisms of GERD
- Reduction in LES tone
- Irritation of esophageal mucosa
- Increased gastric acid secretion
GERD worrisome symptoms
New onset ≥ age 60 years
* Evidence of GI bleeding (or IDA)
* Anorexia/weight loss
* Dysphagia/odynophagia
* Vomiting (obstruction)
* GI cancer in FDR
Risk Factors for Barrett’s Esophagus
Duration of GERD >5-10 years
* Age >50 years
* White, male
* Hiatal hernia
* Obesity
* Tobacco use
* Nocturnal reflux
Antacids
tums
increases ph for about 20-30 min
h2 receptor antagonists
cimetidine, ranitidine, famotidine
decreases acid production for 6-12 hours, relief in 60 min
Proton pump inhibitors
omeprazole
reduces gastric acid secretion
relief in 1-3 days
Acute Cholecystitis
- Inflammation of the gallbladder
- Right upper quadrant pain; sometimes epigastric
- Fever
- Develops in about 6-11% of patients who have gallstones
RUQ pain diff diagnosis
cholecystitis
acute hepatitis
epigastric pain diff diagnosis
pancreatitis
gastric etiology
LUQ pain diff diagnosis
Acute MI
pancreatitis
PUD
GERD
gastritis
splenic etiology
lower abdominal pain diff diagnosis
appendicitis
diverticulitis
nephrolithiasis
pyelonephritis
right lower quadrant pain with fever
crohn’s dx
left lower quadrant pain plus fever
diverticulitis