GI Flashcards
foregut becomes
esophagus to 2nd part of duodenum
midgut becomes…
upper duodenum to proximal 2/3rds transverse colon
hindgut becomes..
distal 1/3rd transverse colon to anal canal above pectinate
when does midgut start rotating and until when
midgut physiologic herniation through UMBILICAL RING at week6 and 270 deree counterclockwise rotation around SMA by week 10
rostral fold closure failure leads to
sternal defects (ectopia cordis)
lateral food closure failure leads to
gastroschisis and omphalocele
caudal fold closure failure leads to
bladder extrophy
most common tracheoesophageal anomaly
esophageal atresia with distal TEF
air enters stomach, vomits with FIRST feeding
double bubble sign associated with down syndrome
duodenal atresia
what does jejunal and ileal atresia lead to
disruption of mesenteric vessels, ischemic necrosis, and segmental resorption (bowel discontinuinity and “apple ppel”
pancreas comes from foregut, midgut, or hindgut?
foregut
origin of pancreatic head
both ventral and dorsal pancreatic bud
origin of uncinate process, and main pancreatic duct
ventral pancreatic duct
origin of pancreatic boy, tail, isthmus, accessory pancreatic duct
dorsa lpancreatic duct
ring of pancreatic tissue that causes narrowing of duodenum
annular pancreas (encircles 2nd part of duodenum)
ventral and dorsal pancreatic tail fails to fuse at 8 weeks
pancreas divisum
mostly asymptomatic, but can cause chronic abdominal pain or pancreatitis
where does spleen arise and what blood supplies
spleen arises from mesentery of stomach (mesodermal) but is supplied by foregut (celiac trunk -> splenic artery)
what makes a GI structure retroperitoneal?
lacks mesentery
what are the retroperitoneal structures
SAD PUCKER suprarenal/adrenal glands aorta/ivc dudoenum (part 2-4) pancreas (everything but tail) ureters colon (ascending and descending parts) kidneys esophagus (thoracic) rectum
what part of duodenum has opening to CBD and pancreatic duct
2nd part
blood supply to foregut
celiac trunk
p and s supply of foregut
parasym - vagus nerve
symp - throacic splanchnic
p and s supply of midgut
para - vagus
symp - thoracic splanchnic
blood supply midgut
SMA
blood supply hindgut
IMA
p and s of hindgut
para - pelvic splanchnic
sym - lumbar splanchnic
besides esophagus and duodenum what else comes from foregut
pharynx, liver gallbladder, pancreas, spleen (tehcnically mesoderm) but gets blood supply from celiac
what is contained in falciform ligament (comes from ventral mesentery)
ligamentum teres hepatis (fetal umbilical vein derivative)
what is contained in hepatoduodenal ligament
portal triad (proper hepatic, common bile duct, portal vein)
what is the pringle manuever
squeezing the hepatoduodenal ligament to control bleeding in omental foramen
which ligament contains gastric arteries
gastro hepatic ligament
what houses the gastro epiploic arteries
gastrocolic ligament
what is contained within splenorenal ligament
splenic artery and vein, tail of pancreas
layers of gut wall from inside to outside
MSMS mucosa submucosa muscularis serosa
which layer of gut wall contains messner nerve plexus and secretes fluid
submucosa
which layer contains myenteric nerve plexus (auerbach) and is responsbile for motility
muscularis
gastric erosion vs gastric ulcer
erosion only affects mucosa
ulcer can invade into submucosa, inner or outer muscular layer
difference in functio between auerbach and meissner’s plexus
meissner plexus (submucosal) only has parasympathetic tone (secretory) whereas auerbach has both
what type of cells reside in esophagus
nonkeratinized stratified squamous
histology of stomach
gastric glands
what are brunner glands and where are they located
hco3 secreting cells of submucosa located in duodenum