GI: 334 - 336 Flashcards
What defines the foregut?
Pharynx to duodenum
What defines the midgut?
Duodenum to proximal 2/3 of transverse colon
What defines the hindgut?
Distal 1/3 of transverse colon to anal canal above the pectinate line
What 3 things that lead to developmental defects of the anterior abdominal wall and what are their associated defects?
- Failure of rostral fold close - sternal defects
- Failure of lateral folds to close - omphalocele, gastroschisis
- Failure of caudal folds to close - bladder exstrophy
What is duodenal atresia due to?
Failure to recanalize
What is duodenal atresia associated with?
Trisomy 21
What causes jejunal, ileal, colonic atresia?
Vascular accident
Explain the two important steps in midgut development.
- Week 6: Midgut herniates through umbilical ring
2. Week 10: Returns to abdominal cavity and rotates around SMA
What is gastroschisis?
Extrusion of abdominal contents through abdominal folds, not covered by peritoneum
What is omphalocele?
Persistence of herniation of abdominal contents into umbilical cord, covered by peritoneum
How does TE fistula typically present?
Drooling, choking, and vomiting with first feeding
What would you see on CXR with a TE fistula?
Air in the stomach
What is a clinical test for TE fistula?
Failure to pass nasogastric tube into stomach
What causes cyanosis in TE fistula?
Laryngospasms which work to avoid reflux-related aspiration
What causes congenital pyloric stenosis?
Hypertrophy (of the pylorus)
How does congenital pyloric stenosis present?
Palpable “olive” mass in epigastric region and nonbilious projectile vomiting at 2-6 weeks
What is the treatment for congenital pyloric stenosis?
Surgical incision