GI: 334 - 336 Flashcards

1
Q

What defines the foregut?

A

Pharynx to duodenum

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2
Q

What defines the midgut?

A

Duodenum to proximal 2/3 of transverse colon

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3
Q

What defines the hindgut?

A

Distal 1/3 of transverse colon to anal canal above the pectinate line

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4
Q

What 3 things that lead to developmental defects of the anterior abdominal wall and what are their associated defects?

A
  1. Failure of rostral fold close - sternal defects
  2. Failure of lateral folds to close - omphalocele, gastroschisis
  3. Failure of caudal folds to close - bladder exstrophy
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5
Q

What is duodenal atresia due to?

A

Failure to recanalize

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6
Q

What is duodenal atresia associated with?

A

Trisomy 21

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7
Q

What causes jejunal, ileal, colonic atresia?

A

Vascular accident

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8
Q

Explain the two important steps in midgut development.

A
  1. Week 6: Midgut herniates through umbilical ring

2. Week 10: Returns to abdominal cavity and rotates around SMA

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9
Q

What is gastroschisis?

A

Extrusion of abdominal contents through abdominal folds, not covered by peritoneum

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10
Q

What is omphalocele?

A

Persistence of herniation of abdominal contents into umbilical cord, covered by peritoneum

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11
Q

How does TE fistula typically present?

A

Drooling, choking, and vomiting with first feeding

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12
Q

What would you see on CXR with a TE fistula?

A

Air in the stomach

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13
Q

What is a clinical test for TE fistula?

A

Failure to pass nasogastric tube into stomach

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14
Q

What causes cyanosis in TE fistula?

A

Laryngospasms which work to avoid reflux-related aspiration

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15
Q

What causes congenital pyloric stenosis?

A

Hypertrophy (of the pylorus)

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16
Q

How does congenital pyloric stenosis present?

A

Palpable “olive” mass in epigastric region and nonbilious projectile vomiting at 2-6 weeks

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17
Q

What is the treatment for congenital pyloric stenosis?

A

Surgical incision

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18
Q

How common is congenital pyloric stenosis?

A

1/600 live births

19
Q

Congenital pyloric stenosis is more common in what subset of patients?

A

Firstborn males

20
Q

What are the different embryological precursors to the pancreas?

A

Pancreas comes from the foregut

Ventral pancreatic buds - form pancreatic head, main pancreatic duct, uncinate process

Dorsal bud - forms body, tail, isthmus, accessory pancreatic duct

21
Q

What are two developmental defects that can occur with the pancreas?

A
  1. Annular pancreas

2. Pancreas divisum

22
Q

What happens in an annular pancreas?

A

Ventral pancreatic bud abnormally encircles 2nd part of the duodenum, forms a ring of pancreatic tissue that may cause duodenal narrowing

23
Q

What happens in pancreas divisum?

A

Ventral and dorsal parts fail to fuse at 8 weeks

24
Q

What does the spleen vs. its blood supply arise from embryologically?

A

Spleen - mesentery of the stomach (mesodermal)

Blood supply - from the foregut (celiac artery)

25
Q

What can injury to retroperitoneal structures lead to?

A

Blood or gas accumulation in retroperitoneal spaces

26
Q

What are the retroperitoneal structures?

A

Mnemonic: SAD PUCKER

Suprarenal (adrenal) glands
Aorta and IVC
Duodenum (2nd through 4th parts)

Pancreas (except tail)
Ureters
Colon (descending and ascending)
Kidneys
Esophagus (lower 2/3)
Rectum (partially)
27
Q

What are 6 important GI ligaments?

A
  1. Falciform
  2. Hepatoduodenal
  3. Gastrohepatic
  4. Gastrocolic
  5. Gastrosplenic
  6. Splenorenal
28
Q

What does the falciform ligament connect?

A

Liver to the anterior abdominal wall

29
Q

What is contained within the falciform ligament?

A

Ligamentum teres hepatis (derivative of fetal umbilical vein)

30
Q

What does the hepatoduodenal ligament connect?

A

Liver to duodenum

31
Q

What does the hepatoduodenal ligament contain?

A

Portal triad: proper hepatic artery, portal vein, common bile duct

32
Q

What does the gastrohepatic ligament connect?

A

Liver to less curvature of the stomach

33
Q

What does the gastrohepatic ligament contain?

A

Gastric arteries

34
Q

What does the gastrocolic ligament connect?

A

Greater curvature of stomach and transverse colon

35
Q

What does the gastrocolic ligament contain?

A

Gastroepiploic arteries

36
Q

What does the gastrosplenic ligament connect?

A

Greater curvature of stomach and spleen

37
Q

What does the gastrosplenic ligament contain?

A

Short gastrics, left gastroepiploic vessels

38
Q

What does the splenorenal ligament connect?

A

Spleen to posterior abdominal wall

39
Q

What does the splenorenal ligament contain?

A

Splenic artery and vein, tail of pancreas

40
Q

Which ligament separates the greater and lesser sacs on the right and why is this important?

A

Gastrohepatic - may be cut during surgery to access the lesser sac

41
Q

What is the Pringle maneuver?

A

Ligament may be compressed between thumb and index finger placed in omental foramen to control bleeding

42
Q

What separates the greater and lesser sacs on the left?

A

Gastrosplenic

43
Q

Which ligament is part of the greater omentum?

A

Gastrocolic ligament