CARDIO 296-297 Flashcards
Name the 2 large vessel vasculities.
Temporal (giant cell) arteritis, Takayasu arteritis
What’s the difference between the location of the vasculities in Temporal vs. Takayasu?
Temporal - more distal (branches of the carotid, e.g. temporal or ophthalmic)
Takayasu - more proximal (in the arch)
Describe the classic patient in temporal (giant cell) arteritis.
Elderly female, usually over 50 years old
Describe 3 symptoms seen in temporal (giant cell) arteritis.
- Unilateral headache (temporal artery)
- Jaw claudication - pain in the jaw or ear while chewing
- Irreversible blindness (ophthalmic artery)
What rheumatic condition is giant cell arteritis associated with?
Polymyalgia rheumatica
What is a classic lab finding in temporal (giant cell) arteritis?
Increased ESR
What does a giant cell look like?
Has multiple nuclei
Where is there fibrosis in temporal (giant cell) arteritis?
Intimal layer
How do we treat temporal (giant cell) arteritis?
High dose corticosteroids - do it quickly to prevent vision loss
Describe the classic patient seen in Takayasu arteritis.
Asian females < 40 years old
How does Takayasu arteritis present?
Mnemonic: TAKAYASU
Temperature (fever)
All over (night sweats)
Kan't see (ocular disturbance)
Arthritis
mYalgia
Aortic arch
Skin nodules
Upper extremity loss of pulses ("pulseless disease")
Name 3 medium-vessel vasculitides.
- Polyarteritis nodosa
- Kawasaki disease
- Buerger disease (thromboangiitis obliterans)
Name 4 small-vessel vasculitides.
- Granulomatosis with polyangiitis (Wegener)
- Microscopic polyangiitis
- Churg-Strauss syndrome
- Henoch-Schonlein purpura
Does polyarteritis nodosa primarily affect younger or older people?
Young adults
What lab result is associated with polyarteritis nodosa?
30% of people are seropositive for hepatitis B
