GI

Question 1

What are the most commonly used NSAID in post-operative colic patient ?
And what are the 3 most important factors to consider for NSAID discontinuation ?

Answer 1

Flunixin and phenylbutazone
Important factor to consider when deciding the timepoint for NSAID discontinuation following colic surgery : absence of active colic sign, pain score evaluation and absence of fever.

A survey of non-steroidal anti-inflammatory drug use in the post-operative period following equine colic surgery
eve 2023

Question 2

What is the Leaky Gut Syndrome (LGS) ?
What are the risk factors for developing LPS ?

Answer 2

**Leaky gut syndrome (LGS) **is an idiopathic disorder characterised by weakening of tight junction proteins (such as zonulin) in the gastrointestinal epithelium. The resulting hyperpermeability of the GI tract can trigger aberrant systemic inflammatory responses.
Combined transport and exercise increases gastrointestinal permeability and systemic SAA and LPS.

The combination of trailer transport and exercise increases gastrointestinal permeability and markers of systemic inflammation in horses
EVJ 2023