Respi Flashcards
What is the best staining method for identification of mast cells in BALF ?
Recommendation for BAL cytology staining would be to use both the MGG and the Toluidine Blue staining method, relying on the Toluidine Blue for the enumeration of mast cells.
Reliability of cytological evaluation of mast cells from bronchoalveolar lavage uid in horses: Intraobserver agreement and mast cell identi cation
eve 2020
Is oiled mixed hay feeding system effective in controlling the airway obstruction in SEA horses ?
Nutri-Foin Système, which incorporates soybean oil to mechanically processed hay, is an appropriate alternative to pelleted hay for the control of the airway obstruction in horses with SEA.
Effects of a propriety oiled mixed hay feeding system on lung function, neutrophilic airway inflammation and oxidative stress in severe asthmatic horses
evj 2020
Does intra-articular administration of methylprednisolone effective in improving the lung function of SEA horses ?
Methylprednisolone IA administration improves the lung function of severe asthmatic horses. However, this effect was mild and of a short duration.
Pulmonary response of severely asthmatic horses after intra-articular administration of methylprednisolone
evj 2021
Which statement is true about severe equine asthma?
A- Angiogenesis contributes to thickening of the airway wall in asthmatic horses and was reversed by a 2-week treatment with corticosteroids.
B- Contrary to human, angiogenesis does not contribute to thickening of the airway wall in asthmatic horses
C- Angiogenesis contributes to thickening of the airway wall in asthmatic horses and was not reversed by a 2-week treatment with corticosteroids.
D- Angiogenesis contributes to thickening of the airway wall in asthmatic horses and was reversed by a 2-week treatment with bronchodilators.
C- Angiogenesis contributes to thickening of the airway wall in asthmatic horses and was not reversed by a 2-week treatment with corticosteroids.
Bronchial angiogenesis in horses with severe asthma and its response to corticosteroids
jvim 2021
What is the clinical efficacy of nebulized dexamethasone sodium phosphate in the treatment of horses with severe asthma ? Are they side effects ?
Oral, but not nebulized dexamethasone is an
effective therapy for horses with severe asthma and both treatment modalities inhibit the hypothalamic-pituitary-adrenal axis.
Nebulized dexamethasone sodium phosphate in the treatment
of horses with severe asthma
jvim 2021
What is the clinical efficacy of ciclesonide in the treatment of horses with severe asthma ? Are they side effects ?
Ciclesonide inhalation solution administered by the Aservo® EquiHaler® effectively reduced severity of clinical signs in a majority of horses with severe equine
asthma and was well tolerated.
Few systemic and local adverse events of ciclesonide were observed.
Inhaled ciclesonide is efficacious and well tolerated in the treatment of severe equine asthma in a large prospective European clinical trial
evj 2021
Which statement is true about lipidomic analysis of surfactant and plasma from horses with asthma ?
A- The most significant surfactant alterations were present in MEA (altered phospholipid content and composition)
B- The most significant surfactant alterations were present in SEA (altered phospholipid content and composition)
C- Serum SP-D concentrations were only significantly increased in MEA horses
D- Serum SP-D concentrations were significantly increased in MEA and SEA horses
Answer B
The most significant surfactant alterations were present in SEA (altered phospholipid content and composition).
Only SEA horses had significantly increased serum SP-D concentrations.
Lipidomic analysis of surfactant and plasma from horses with asthma and age-matched healthy horses
AJVR 2022
Which environment maximise the exposition to fungi ?
A- Pasture
B- Stabling
C- Truck
Stabling increases exposure to fungi.
Exposure to fungi could contribute to airway inflammation by increasing dectin-1 functional isoforms.
Characterization of fungal exposure and dectin-1 expression in healthy horses and horses with severe asthma
AJVR 2022
Which statement is true about severe equine asthma?
A- SEA is associated with lower airway innervation
B- SEA is associated with greater airway innervation
C- Airway innervation is modified only in SEA but not in MEA
D- Airway innvervation is not significantly different between SEA and control horses.
Severe asthma in horses is associated with greater airway innervation, possibly contributing to airway smooth muscle remodeling and exacerbating severity of the disease.
Severe asthma in horses is associated with increased airway innervation
jvim 2024
What are the benefits of soaked hay in SEA horses ?
A- Soaked hay decreases respirable particles, but does not improve lung function.
B- Soaked hay decreases respirable particles and lung resistance
C- Soaked hay decreases respirable particles for 6 hours
D- 2 hours of soaking are necessary to reduce respirable particles from hay
Soaking hay for 10 or 30 minutes reduces respirable particles by up to 90% for a period of 1 to 2 hours.
Soaked hay can decrease lung resistance and control airway obstruction in horses with severe asthma.
In the study : soaked hay was immersed for 45 minutes and dried out hay was discarded between meals.
Effects of soaked hay on lung function and airway inflammation in horses with severe asthma
jvim 2024
Which bronchodilator has the best efficacy and fewer side effects in horses with SEA ?
Comparison between hyoscine butylbromide (HBB) = N-butylscopolammonium bromide (ESTOCELAN®) and salbutamol (VENTOLINE®).
Both drugs have a similar bronchodilator potency but with a longer duration for salbutamol. Gastrointestinal and cardiovascular side effects were noted only with HBB, suggesting the preferential use of salbutamol to relieve bronchoconstriction in horses with asthma.
Comparative study of the bronchodilator efficacy and adverse effects of salbutamol and hyoscine butylbromide in horses with severe asthma
jvim 2024
Which statement is true about microarray molecular mapping of horses ?
A- Microarray profiling cannot identify specific allergenic components associated with SEA.
B- Microarray profiling can identify specific allergenic components associated with SEA, with a variability of sensitization profiles between geographical locations.
C- Microarray profiling can identify specific allergenic components associated with SA in horses, regardless of location.
D- Microarray profiling can identify specific allergenic components associated with SEA, with a variability of sensitization profiles between seasons.
B- Microarray profiling can identify specific allergenic components associated with SEA in horses, with a variability of sensitization profiles between geographical locations.
Microarray molecular mapping of horses with severe asthma
jvim 2024
