GI Flashcards

1
Q

Hepatomegaly

A

AL Amyloidosis

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2
Q

Functional hypospenim

A

AL amyloidosis

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3
Q

Liver abscess testing

A
  1. 1,3-B-D-glucan
    2.MTB, HIV, Epstein Barr, CMV, hepB,C
  2. Chlamydia psittaci,coxiella burnetti
  3. Brucellosis, bartonellosis, malaria listeriosis, histoplasmosis, babesiosis,cocci,crypto, blastomycosis, malaria, toxo, rpr, ehrlichosis, lyme, anaplasmosis
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4
Q

Non cirrhotic portal hypertension in adults

A

Nodular regenerative hyperplasia

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5
Q

Nodular regenerative hyperplasia

A

Causes hypersplenism , splenic sequestration related cytopenias, infections, pulmonary arterial hypertension, hepatopulmonary syndrome

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6
Q

Nodular regenerative hyperplasia,

A

Arises from:
1. Common variable immunodeficiency
2. Combined immunodeficiency’s
3. Phagocytes defect
4, chronic granulomatous disease

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7
Q

Nodular regenerative hyperplasia in immunodeficiency

A

Occurs with inflammatory complications:
1. High levels of bacterial DNA
2. Soluble CD14
3. Interferon -y activity (higher is worse)

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8
Q

Cirrhosis (thrombocytopenia is not a predictor of procedural bleeding)
JTH 2024;22 2653-2669

A
  1. Increased levels of willebrand factor
  2. Decreased ADAMTS-13
  3. Decreased production protein S,C, antithrombin
  4. Hypofibrinogemia
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9
Q

Fecal elastase

A

Pancreatic insufficiency

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10
Q

Vasoactive tumor

A

Diarrhea weight loss

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11
Q

Over the scope clip

A

Brisk bleeding

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12
Q

Hemostatic powder (sterile clay)

A

Good for tumors
Malignant bleeding

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13
Q

Hemostatic powder (sterile clay)

A

Good for tumors
Malignant bleeding

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14
Q

AJG 2023; 118:208-231
LGIB MANAGEMENT

A
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15
Q

Management of anticoagulant and ant platelets in GI bleed
AJG2-22;117-542-548
VKA, DOAC, P2Y12

A

Reverse AC if unstable
Keep aspirin if cardiovascular rx

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16
Q

Transfusion in cirrhosis
Hub>7
No FFP
NO PLT transfusion
Increases portal pressure

A

Kaplan et al HEPATOLOGY 2024
Odutayo, et al Lancet Gastro Hep 2017

17
Q

Polyethylene glycol 3350 electrolyte solution for hepatic encephalopathy

A

Better than Lactulose RAHIMI JAMA IM 2014 for hepatic encephalopathy

18
Q

HEPATORENAL SYNDROME

A

Terlipressin plus. Albumin
Avoid in spO2 < 90%
Avoid ischemia