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MedicalCNS > Rheumatology Interleukin > Flashcards

Rheumatology Interleukin Flashcards

1
Q

PMR

A

IL 6 inhibitions

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2
Q

Psoriasis

A

IL 17, IL 23

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3
Q

Lupus nephritis treatment

A
  1. Steroids
  2. Cyclophosphamide or mycophenolate
  3. Voclospirin or belimumab
    Future: CART cell w/ obinutuzumab
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4
Q

Scleroderma

A

I’m 6 inhibitors (Tocilizumab)
Tyrosine kinase inhibition ILD

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5
Q

Cytokine Release syndrome
Teclistamab may cause

A

Fever, rash, arthralgias, SIRS (alveolitis, aki,hepatitis, hypotension),
Neurological dysfunction)
Elevated inflammatory markers
TNF alpha elevation
IFNy

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6
Q

CYTOKINE RELEASES SYNDROME CAUSES

A

Teclistamab may cause it Usedin MM

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7
Q

CYTOKINE STORM

A
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8
Q

Gout to
Steroids
NSAIDs
Colchicine ( only for the acute setting)

A

Anakinra 100 mg sc daily x5 days

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9
Q

Preventing gout flare
Do not stop

A

Alloputinol
Febuxostat
Colchicine (unless myopathy, cytopenia, neuropathy)

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MedicalCNS (37 decks)

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