CHF Flashcards
HFrEF
LVEF < 40%
HFmrEF
LVEF 41-49%
HFimpEF
LVEF > 40%
HFpEF
LVEF> 50%
Rx HFrEF
ARNI OR ACE/ARB
BETA BLOCKER
MRA
SGLT2
Diuretic PRN
NYHA III -IV African Americans
Hydralazine NITRATES
NYHA I-III LVEF < 35%
ICD
NYHA I-III LVEF <35 %
NSR QRS >150ms w/ LBBB
Cardiac resynchronization w/ dual chamber pacemaker.
4 pillars of HFrEF
ARNI
BB
MRA
SGLT2 inhibitor
Fifth pillar HF HFpEF
Semaglutide
Glucagon like peptide 1 receptor agonist
5th pillar HF
Semaglutide
glucagon-like peptide-1 receptor agonists (GLP-1 RAs).
GLP1
Reduces adipose
Decrease body weight
Decrease inflammation
GLPR1 protects against HF
Decreases LV Remodeling
Decrease TNF
DECREASE CARDIAC FIBROSIS
Myocarditis
May be caused by immune check point inhibitors
JAMA review Enrico Ammirati MD
APRIL 4, 2023 vol 329 number 13