GFR, RBF Flashcards
Describe pressures in renal vasculature
Afferent resistnace is lower than systemic arterioles, Glomerular cap pressure is higher than systemic, Peritubular cap hydro pressure is low and onc is higher
what starling forces change along glom. cap
the cap oncotic pressure goes up. so Puf goes down
what is the normal GFR
125 ml/min
how does GFR change with efferent arteriolar constriction
goes up due to rising Pgc then goes down due to decreasing RPF
Two theories for renal autoregulation
Myogenic: ^ transmural pressure leads to vasoconstriction. Tubuloglomerular: ^ flow sensed by JGA (as ^ NaCl) leads to afferent constriction via adenosine
equation for Renal Plasma flow
RBFx(1-Hct)
Formula for clearance
[Ux(V)]/Px
How does inulin excretion and clearance vary with increasing P[inulin]
excretion increases linearly. clearance remains constant