Geriatrics Flashcards
Older adult age
-over 60
Pharm services in LTC
-review and identify drug therapy probs
-ensure accurate monitoring
-educate patients
Meds w fall risk
-sedatives/hypnotics
-antipsychotics/neuroleptics
-antidepressants
-opiods
-loop diuretics
-a-blockers
Med probs in older adults
-polypharmacy
-nonadherance
-altered PK
Physiologic changes w aging
-dec body water and mass
-inc fat
-dec barorecepter response!!!
-dec HR variability!!!!
-dec hepatic and renal flow
-dec neurotransmitter volume (sensitive to CNS effects)
PK of water soluble drugs in aging
-dec distribution
-inc concentration
-Atenolol
PK of lipid soluble drugs in aging
-inc Vd
-inc half life
-Rifampin
PK of hepatic/renally-cleared drugs in aging
-dec clearance
-inc half-life
-propranolol hepatic
-atenolol propranolol
Beers criteria
-65+
-evaluate risk of meds for old ppl
Required reading
-Beer
Meds considered by Beers
-anticholinergics (cognitive)
-sedatives/CNS effects
-diabetic agents (sulfonylureas)
-meds that might make chronic illness worse
How are decisions about recommendations decided
Who involved in decision making
what types of lit evaluated
how does committee decribe quality of eveidence