geri pharm considerations Flashcards
Age-related changes in older adults can result in a decreased drug effect for all of the following except:
Inhaled muscarinic antagonists
Warfarin
DHP calcium channel blockers
Beta2-agonists
warfarin
For a patient who is >60 years old, with hepatic impairment, or taking concomitant cimetidine, the recommended daily dose of citalopram should not exceed:
10 mg
20 mg
40 mg
60 mg
20mg
Which of the following psychotropic medications would be preferred in the elderly due to its low anticholinergic and sedation effect?
Amitriptyline
Nortriptyline
Sertraline
Paroxetine
sertraline
Accordi The A1C goal for older adults who are frail or with limited anticipated life expectancy of ≤5 years is:
≤6.5%
≤7.0%
≤8.0%
≤9.0%
≤8.0%
Age-related changes in the elder include all of the following except:
Decrease in relative kidney weight
Body weight as fat increases for both men and women
Increase in serum albumin
Decrease in percent body weight as water
Increase in serum albumin
Potential adverse effects from medications with significant anticholinergic effect include all of the following except:
Hypothermia
Dry mouth, skin
Blurred vision
Urinary retention
Hypothermia
Absorption of which of the following is least affected by long-term PPI use?
Iron
Calcium citrate
Vitamin B12
Magnesium
Calcium citrate
PPIs such as lansoprazole, omeprazole and esomeprazole are all inhibitors of CYP450:
3A4
2C19
1A2
2D6
2C19
TMP-SMX should be avoided in elders who are being concomitantly treated with:
Moderate- to high-intensity statin therapy
ARBs or ACEIs
2nd-generation antihistamine
SSRIs
ARBs or ACEIs
For an 87-year-old man with a history of cardiovascular disease and requires an LDL-C reduction of approximately 33%, the NP recommends:
Initiating atorvastatin 20 mg daily
Initiating rosuvastatin 20 mg daily
Initiating simvastatin 10 mg daily
No statin therapy as there is likely no significant benefit at his age
Initiating atorvastatin 20 mg daily
